Results 71 to 80 of about 6,251,756 (328)

The role of public health networks in strengthening public health systems: the case of EMPHNET in the Eastern Mediterranean region

Frontiers in Public Health
The Eastern Mediterranean Region (EMR) faces a range of complex public health challenges, including endemic diseases, recurrent outbreaks, and weak health systems exacerbated by political instability and humanitarian crises. Public health networks play a
Yousef Khader, Dana Shalabi, Leen Daoud, Deema Al Bakri, Rana AlHamawi, Randa K. Saad, Sayed Himatt, Zeina Abdel Majeed, Ruba Kamal Alsouri, Nada Ahmed, Rabi Assaf, Nadine Haddad, Sardar Parwiz, Majd A. Alsoukhni, Haitham Bashier, Magid Al-Gunaid, Mohannad Al Nsour   +16 more
doaj   +1 more source

ummary of Canadian Immunization Committee (CIC) Recommendations for Human Papillomavirus Immunization Programs.

Canada communicable disease report = Releve des maladies transmissibles au Canada, 2014
There are over 100 different types of human papillomavirus (HPV), and many have been linked to cancers and benign lesions of the anogenital tract, head, and neck.

semanticscholar   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

“Vaccinating a child is upon the woman”: implications for improving uptake for the recently introduced second dose of measles-containing vaccine based on a rapid community assessment in Uganda

Frontiers in Global Women's Health
BackgroundCaregiver barriers to accessing immunizations are a key factor influencing childhood vaccination. In preparation for the rollout of the second dose measles-containing vaccine (MCV2) in Uganda in October 2022, we aimed to identify possible ...
Adelline Twimukye, Nessa Ryan, Flavia Vivian Najjuma, Yvette Wibabara, Judith Nanyondo, Shillah Nakato, Maria Sarah Nabaggala, Ciara Sugerman, Daniel Kadobera, Rita Atugonza, John Kamulegeya, Joseph Magoola, Racheal Beyagira, Mohammed Lamorde, Alex Riolexus Ario, Alfred Driwale, Shibani Kulkarni   +16 more
doaj   +1 more source

Dentist in mission indradhanush: A target-to-target India's unvaccinated children

Dentistry and Medical Research, 2017
Introduction: Immunization is one of the most effective, safest, and efficient public health interventions and was first introduced in India in 1978. While the impact of immunization on childhood morbidity and mortality has been great, its full potential
Ravneet Malhi, P Basavaraj, Ashish Singla, Ritu Gupta, Venisha Pandita, Vaibhav Vashishtha   +5 more
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Attacking the public health crisis of hepatocellular carcinoma at its roots

Hepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee, Steven D. Lidofsky, Tamar H. Taddei, Lisa J. Townshend‐Bulson   +3 more
wiley   +1 more source

Compliance with the vaccination schedule in children hospitalized with pneumonia and associated factors

Revista de Saúde Pública, 2018
OBJECTIVE: To verify the adequacy and factors associated with compliance with the immunization schedule (BCG, DTP-Hib, MMR, PCV-10) in children hospitalized with pneumonia at a pediatric referral hospital in Northeast Brazil.
Amanda Tabosa Pereira da Silva, Eduardo Jorge da Fonseca Lima, Maria de Fátima Costa Caminha, Andresa Tabosa Pereira da Silva, Edil de Albuquerque Rodrigues Filho, Carmina Silva dos Santos   +5 more
doaj   +1 more source