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Quantum Plasmonic Immunoassay Sensing [PDF]

open access: yesNano letters (Print), 2019
Plasmon-polaritons are among the most promising candidates for next generation optical sensors due to their ability to support extremely confined electromagnetic fields and empower strong coupling of light and matter. Here we propose quantum plasmonic immunoassay sensing as an innovative scheme, which embeds immunoassay sensing with recently ...
N. Kongsuwan   +6 more
arxiv   +3 more sources

Hormone Immunoassay Interference: A 2021 Update

open access: yesAnnals of Laboratory Medicine, 2022
Immunoassays are powerful qualitative and quantitative analytical techniques. Since the first description of an immunoassay method in 1959, advances have been made in assay designs and analytical characteristics, opening the door for their widespread ...
K. Ghazal   +3 more
semanticscholar   +1 more source

Fermentation, Purification, and Tumor Inhibition of a Disulfide-Stabilized Diabody Against Fibroblast Growth Factor-2

open access: yesFrontiers in Oncology, 2021
Angiogenesis is considered one of the hallmarks of cancer and plays a critical role in the development of tumor. Fibroblast growth factor 2 (FGF-2) is a member of the FGF family and participates in excessive cancer cell proliferation and tumor ...
Simin Zhang   +11 more
doaj   +1 more source

Preparation of DSPE-PEG-cRGD Modified Cationic Liposomes for Delivery of OC-2 shRNA and The Antitumor Effects on Breast Cancer

open access: yesPharmaceutics, 2022
Cationic liposome delivery of interfering RNA (shRNA) plays an important role in tumor therapy. The cyclic Arg-Gly-Asp (cRGD) modified cationic liposomes (cRGD-CL) were designed for targeted delivery of ONECUT2 (OC-2) shRNA (pshOC-2) to breast cancer ...
Chunyan Liu   +5 more
doaj   +1 more source

Development, Validation and Application of a Bridging ELISA for Detection of Antibodies against GQ1001 in Cynomolgus Monkey Serum

open access: yesMolecules, 2023
Immunogenicity is a major issue associated with the PK, efficacy, and safety evaluation of therapeutic protein products during pre-clinical and clinical studies. A multi-tiered approach consisting of screening, confirmatory, and titration assays has been
Tingting Liu   +12 more
doaj   +1 more source

Development of an accurate lateral flow immunoassay for PEDV detection in swine fecal samples with a filter pad design

open access: yesAnimal Diseases, 2021
Porcine epidemic diarrhea virus (PEDV), as the main causative pathogen of viral diarrhea in pigs, has been reported to result in high morbidity and mortality in neonatal piglets and cause significant economic losses to the swine industry. Rapid diagnosis
Siyi Zou   +7 more
doaj   +1 more source

Decision Tree for Protein Biomarker Selection for Clinical Applications [PDF]

open access: yesIn: Islam Williams, T. (eds) Tissue Proteomics. Methods in Molecular Biology, vol 2884. Humana, New York, NY (2025), 2023
Discovery of novel protein biomarkers for clinical applications is an active research field across a manifold of diseases. Despite some successes and progress, the biomarker development pipeline still frequently ends in failure as biomarker candidates cannot be validated or translated to immunoassays.
arxiv   +1 more source

Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of Mycobacterium tuberculosis through induction of autophagy and augment anti-TB activity of isoniazid in RAW 264.7 macrophages

open access: yesFrontiers in Immunology, 2023
Rapid emergence of antibiotic resistance in tuberculosis has left us with limited resources to treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the development of novel therapeutics.
Pramod Kumar Gupta   +6 more
doaj   +1 more source

Development of a Point-of-Care System Based on White Light Reflectance Spectroscopy: Application in CRP Determination

open access: yesBiosensors, 2021
The development of methods and miniaturized systems for fast and reliable quantitative determinations at the Point-of-Care is a top challenge and priority in diagnostics.
Dimitra Tsounidi   +10 more
doaj   +1 more source

Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer

open access: yesFrontiers in Oncology, 2020
Tumor angiogenesis plays an important role in the progression and metastasis of ovarian cancer. EGFL6 protein is highly expressed in ovarian cancer and has been proposed to play an important role in promoting tumor angiogenesis.
Wenhui Zhu   +6 more
doaj   +1 more source

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