Results 91 to 100 of about 322,348 (369)

Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following Surgery in a Clinical Pilot

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Staphylococcus aureus osteomyelitis remains a very challenging condition; recent clinical studies have shown infection control rates following surgery/antibiotics to be ~60%. Additionally, prior efforts to produce an effective S.
Shardulendra Prasad Sherchand   +9 more
doaj   +1 more source

Advection-enhanced kinetics in microtiter plates for improved surface assay quantitation and multiplexing capabilities [PDF]

open access: yesarXiv, 2022
Surface assays such as ELISA are pervasive in clinics and research and predominantly standardized in microtiter plates (MTP). MTPs provide many advantages but are often detrimental to surface assay efficiency due to inherent mass transport limitations. Microscale flows can overcome these and largely improve assay kinetics.
arxiv  

An ultrasensitive polydopamine bi-functionalized SERS immunoassay for exosome-based diagnosis and classification of pancreatic cancer† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01611a

open access: yesChemical Science, 2018
Ultrasensitive polydopamine bi-functionalized surface enhanced Raman scattering immunoassay expedites exosome-based diagnosis and classification of pancreatic cancer.
Tengda Li   +7 more
semanticscholar   +1 more source

Leveraging Design of Experiments to Unravel the Amplification Mechanism of Single‐Molecule Wide‐Field Biosensors

open access: yesAdvanced Materials Interfaces, EarlyView.
Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio   +9 more
wiley   +1 more source

Development of a highly sensitive noncompetitive electrochemical immunosensor for the detection of atrazine by phage anti-immunocomplex assay [PDF]

open access: yes, 2014
The development of immunosensors for the detection of small molecules is of great interest because of their simplicity, high sensitivity and extended analytical range.
Arevalo, Fernando Javier   +5 more
core   +1 more source

Magnetic Nanoparticle Relaxation Dynamics-based Magnetic Particle Spectroscopy (MPS) for Rapid and Wash-free Molecular Sensing [PDF]

open access: yes, 2019
Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP relaxation dynamics-based magnetic particle spectroscopy (MPS) method for the quantitative detection of molecular ...
arxiv   +1 more source

Nanozyme-Mediated Dual Immunoassay Integrated with Smartphone for Use in Simultaneous Detection of Pathogens.

open access: yesACS Applied Materials and Interfaces, 2017
Nanozymes are an excellent class of optical reporters for the development of sensitive biosensors for widespread applications. In this study, mesoporous core-shell palladium@platinum (Pd@Pt) nanoparticles were synthesized and then applied as signal ...
Nan Cheng   +11 more
semanticscholar   +1 more source

Antifouling PEG Coatings by Thiol‐Acrylate Conjugate Addition Reactions for Generation of Protein Patterns via Photobleaching‐Induced Protein Binding (PiPB) BioBitmaps Using Maskless Projection Lithography

open access: yesAdvanced Materials Interfaces, EarlyView.
Homo‐bifunctional PEG, acrylate‐PEG‐acrylate (PEGDA), coatings are prepared on glass and glass‐type surfaces using solvent‐free thiol‐acrylate conjugate addition reactions at room temperature. The prepared PEGDA coatings are stable, antifouling, and provide feature terminal acrylates that can act as free radical acceptors for photobleaching‐induced ...
Ali Usama   +11 more
wiley   +1 more source

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma [PDF]

open access: yes, 2016
Serum protein fingerprints associated with MGUS and MM and their changes in MM after autologous stem cell transplantation (MM-ASCT, day 100) remain unexplored.
Fillerová, Regina   +9 more
core   +1 more source

Design and Simple Assembly of Gold Nanostar Bioconjugates for Surface-Enhanced Raman Spectroscopy Immunoassays

open access: yesNanomaterials, 2019
Immunoassays using Surface-Enhanced Raman Spectroscopy are especially interesting on account not only of their increased sensitivity, but also due to its easy translation to point-of-care formats.
Maria João Oliveira   +8 more
doaj   +1 more source

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