Results 191 to 200 of about 202,164 (266)

Computational Intelligence Accelerates CRISPR‐Cas‐Based Diagnostic Design

open access: yesiLABMED, EarlyView.
Computational intelligence, including pangenome‐guided target mining, machine‐learning‐based guide RNA optimization, and autonomous AI agents, is shifting CRISPR diagnostic design from empirical screening to systematic, data‐driven engineering and accelerating the path from pathogen discovery to deployable diagnostics.
Hengyu Wang   +3 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

open access: yesInterdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang   +10 more
wiley   +1 more source

Digital Immunoassays for Sensitive Quantification of Blood Biomarkers Using Solid-State Nanopores. [PDF]

open access: yesACS Nano
He L   +7 more
europepmc   +1 more source

A broadly applicable split-luciferase biosensor approach for rapid antibody detection in emerging infectious diseases. [PDF]

open access: yesAppl Microbiol Biotechnol
Li X   +9 more
europepmc   +1 more source

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