Results 31 to 40 of about 490 (133)

Activation of cGAS‐STING by Lethal Malaria N67C Dictates Immunity and Mortality through Induction of CD11b+Ly6Chi Proinflammatory Monocytes

Advanced Science, Volume 9, Issue 22, August 5, 2022., 2022
Cyclic GMP‐AMP synthase (cGAS) and stimulator of interferon genes (STING) play critical roles in innate immunity against infectious diseases, while the mechanisms that cGAS‐STING‐induced cytokines suppress immune response against malaria infection remain poorly understood.
Yang Du, Yien Luo, Zhiqiang Hu, Jiansen Lu, Xin Liu, Changsheng Xing, Jian Wu, Tianhao Duan, Junjun Chu, Helen Y. Wang, Xin‐zhuan Su, Xiao Yu, Rong‐Fu Wang   +12 more
wiley   +1 more source

Advanced application of porcine intramuscular adipocytes for evaluating anti-adipogenic and anti-inflammatory activities of immunobiotics. [PDF]

PLoS ONE, 2015
We previously established a clonal porcine intramuscular preadipocyte (PIP) line and we were able to establish a protocol to obtain functional mature adipocytes from PIP cells.
Masahiko Suzuki, Asuka Tada, Paulraj Kanmani, Hitoshi Watanabe, Hisashi Aso, Yoshihito Suda, Tomonori Nochi, Kenji Miyazawa, Kazutoyo Yoda, Fang He, Masataka Hosoda, Tadao Saito, Julio Villena, Haruki Kitazawa   +13 more
doaj   +1 more source

The Beneficial Role of Probiotic Lactobacillus in Respiratory Diseases

Frontiers in Immunology, 2022
Respiratory diseases cause a high incidence and mortality worldwide. As a natural immunobiotic, Lactobacillus has excellent immunomodulatory ability. Administration of some Lactobacillus species can alleviate the symptoms of respiratory diseases such as ...
Tingfeng Du, Aihua Lei, Naiyu Zhang, Cuiming Zhu   +3 more
doaj   +1 more source

Immunoregulatory effects triggered by immunobiotic TL2937 strain involve efficient phagocytosis in porcine antigen presenting cells [PDF]

, 2016
Background: Immunobiotic Lactobacillus jensenii TL2937 modulates porcine mononuclear phagocytes from Peyer?s patches (PPMPs) and induces a differential production of pro- and anti-inflammatory cytokines in response to Toll-like receptor (TLR)-4 ...
Takahashi, Takuya, Saito, Tadao, Sou Ohkawara, Seiya Makino, Iida, Hikaru, Tsukida, Kohichiro, Nochi, Tomonori, Villena, Julio Cesar, Hikaru Iida, Ohkawara, Sou, Tomonori Nochi, Paulraj Kanmani, Kohichiro Tsukida, Hisashi Aso, Ohwada, Shuichi, Tadao Saito, Suda, Yoshihito, Takuya Takahashi, Hiroshi Kano, Yoshihito Suda, Julio Villena, Kano, Hiroshi, Kitazawa, Haruki, Shuichi Ohwada, Aso, Hisashi, Kanmani, Paulraj, Haruki Kitazawa, Makino, Seiya   +27 more
core   +1 more source

Modulation of the inflammation-coagulation interaction during pneumococcal pneumonia by immunobiotic Lactobacillus rhamnosus CRL1505: role of Toll-like receptor 2 [PDF]

, 2014
This study evaluated the effect of nasally administered Lactobacillus rhamnosus CRL1505 on the immuno-coagulative response during pneumococcal infection in immunocompetent mice.
Zelaya, María Hortensia del Rosario, Villena, Julio Cesar, Gramajo Lopez, Andres Daniel, Agüero, Graciela, Alvarez, Gladis Susana   +4 more
core   +1 more source

Immunoregulatory effect of bifidobacteria strains in porcine intestinal epithelial cells through modulation of ubiquitin-editing enzyme A20 expression. [PDF]

PLoS ONE, 2013
BACKGROUND: We previously showed that evaluation of anti-inflammatory activities of lactic acid bacteria in porcine intestinal epithelial (PIE) cells is useful for selecting potentially immunobiotic strains. OBJECTIVE: The aims of the present study were:
Yohsuke Tomosada, Julio Villena, Kozue Murata, Eriko Chiba, Tomoyuki Shimazu, Hisashi Aso, Noriyuki Iwabuchi, Jin-zhong Xiao, Tadao Saito, Haruki Kitazawa   +9 more
doaj   +1 more source

Differential Expression of Mitosis and Cell Cycle Regulatory Genes during Recovery from an Acute Respiratory Virus Infection

Pathogens, 2021
Acute respiratory virus infections can have profound and long-term effects on lung function that persist even after the acute responses have fully resolved. In this study, we examined gene expression by RNA sequencing in the lung tissue of wild-type BALB/
Ajinkya R. Limkar, Justin B. Lack, Albert C. Sek, Caroline M. Percopo, Kirk M. Druey, Helene F. Rosenberg   +5 more
doaj   +1 more source

Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro

Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019
Hepatic inflammation and injury may result from the translocation of pathological bacteria and their proinflammatory mediators. Probiotics attenuate hepatic diseases related to inflammation by exhibiting immunoregulatory effects. Therefore, this study was conducted to evaluate lipid reduction and immunoregulatory potentials of probiotic bacteria in ...
Paulraj Kanmani, AbuZar Ansari, Julio Villena, Hojun Kim, Senthamil R. Selvan   +4 more
wiley   +1 more source

[Retracted] Preventative and Therapeutic Probiotic Use in Allergic Skin Conditions: Experimental and Clinical Findings

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
Probiotics are ingested live microbes that can modify intestinal microbial populations in a way that benefits the host. The interest in probiotic preventative/therapeutic potential in allergic diseases stemmed from the fact that probiotics have been shown to improve intestinal dysbiosis and permeability and to reduce inflammatory cytokines in human and
Öner Özdemir, Azize Yasemin Göksu Erol, Ibrahim Banat   +2 more
wiley   +1 more source

Dolosigranulum pigrum Modulates Immunity against SARS-CoV-2 in Respiratory Epithelial Cells

Pathogens, 2021
In a previous work, we demonstrated that nasally administered Dolosigranulum pigrum 040417 beneficially modulated the respiratory innate immune response triggered by the activation of Toll-like receptor 3 (TLR3) and improved protection against ...
Md. Aminul Islam, Leonardo Albarracin, Vyacheslav Melnikov, Bruno G. N. Andrade, Rafael R. C. Cuadrat, Haruki Kitazawa, Julio Villena   +6 more
doaj   +1 more source