Results 101 to 110 of about 174,366 (328)

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

open access: yesAdvanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera   +10 more
wiley   +1 more source

Immunocytochemistry [PDF]

open access: yes, 2020
Melinda S. Camus   +2 more
  +4 more sources

Ascites as a subject of studies in ovarian cancer

open access: yesСибирский онкологический журнал, 2019
Ovarian cancer is a highly heterogeneous disease characterized by multiple histological subtypes. High- grade serous ovarian carcinoma is the most common histological subtype of ovarian cancer.
A. B. Villert   +3 more
doaj   +1 more source

Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization [PDF]

open access: yes, 2007
rom the identification of genes to the characterization of their functions and interactions. Developmental biologists have long used whole mount in situ hybridization (WISH) to determine gene expression patterns, as a vital tool for formulating and ...
Davis   +7 more
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Leishmania major: Parasite Interactions Suggesting Sexuality

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
In five experiments, Leishmania (Leishmania) major (MRHO/SU/59/P-strain) grew poorly when seeded in FYTS medium supplemented with 15% fetal calf serum, but presented several peculiar pairs of promastigotes diametrically opposed and attached at their ...
Sousa Maria Auxiliadora de   +2 more
doaj  

Differential expression and subcellular localization of BmHMGA in silkworm (Bombyx mori)

open access: yes浙江大学学报. 农业与生命科学版, 2014
The high mobility group A (HMGA) proteins have a close relation with chromatin remodeling and cancer transformation. They are widely expressed during embryogenesis, whereas their expression is absent or very low in adult tissues.
Zhang Haihua   +8 more
doaj   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Immunocytochemistry v1

open access: yes
This protocol describes how to perform immunocytochemistry on fixed cells.
Arun Thiruvalluvan, Agnete Kirkeby
  +5 more sources

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