Results 111 to 120 of about 166,510 (294)

Microtubule heterogeneity of Ornithogalum umbellatum ovary epidermal cells: non-stable cortical microtubules and stable lipotubuloid microtubules

Folia Histochemica et Cytobiologica, 2011
Lipotubuloids, structures containing lipid bodies and microtubules, are described in ovary epidermalcells of Ornithogalum umbellatum. Microtubules of lipotubuloids can be fixed in electron microscope fixativecontaining only buffered OsO4 or in ...
Maria Kwiatkowska, Dariusz Stępiński, Justyna T. Polit, Katarzyna Popłońska, Agnieszka Wojtczak   +4 more
doaj  

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Proliferation in Minimal Invasive Samples of Canine Lymphomas: Ki67 Index in Previously Stained Cytology and Paired Cell Blocks

Veterinary Sciences
Canine lymphoma (CL) is a heterogeneous neoplasm with varying prognoses, and Ki67 expression is a key marker for assessing tumor proliferation. This study aimed to compare Ki67 immunostaining in cytology smears (PSCS) and cell blocks (CBs) of canine ...
Filipe Sampaio, Carla Marrinhas, Luísa Fonte-Oliveira, Ricardo Marcos, Pedro N. Oliveira, Marta Santos   +5 more
doaj   +1 more source

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

The Value of Thin Layer Cytology in Cancer Patients’ Pericardial Effusions

Current Oncology
Objective: Early diagnosis and treatment of metastatic pericardial disease are crucial to prevent the life-threatening complication of cardiac tamponade. Thin Layer Cytology (TLC), a widely adopted technique in cytology, has gained significant acceptance
Christos Lafaras, Evdokia Mandala, Kyranna Lafara, Ioannis Kalafatis, Thomas Achladas, Vasiliki Koukoulitsa, Chrysoula Gouta, Theodora Tsiouda, Soultana Skevoudi   +8 more
doaj   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

British Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin, Gabriela Hurtado‐Alvarado, Lilla Barna, Arturo Contis‐Montes de Oca, Rocío Ruíz‐Manzano, Krisztián Laczi, András Kincses, Gergő Porkoláb, Gang Chen, Beatriz Gómez‐González, Mária A. Deli   +10 more
wiley   +1 more source

Detection of HSP27-like molecules in the annelid Enchytraeus japonensis after exposure to extremely low frequency magnetic fields (50 Hz)

Invertebrate Survival Journal, 2007
The immunocytochemical study performed on the annelid Enchytraeus japonensis revealed the presence of immunoreactive heat shock protein (HSP)27 molecules in different areas of the body.
D Malagoli, M Marchetti, F Gobba
doaj  

Ultrarapid BRAF mutation detection on supernatant cell-free DNA obtained by FNA: An accurate and expedient method for BRAF assessment in aggressive thyroid carcinomas. [PDF]

Cancer Cytopathol
Abstract Background For patients with aggressive thyroid cancer, including anaplastic thyroid carcinoma (ATC) and high‐grade follicular cell‐derived non‐anaplastic thyroid carcinoma, rapid BRAF p.V600E testing is critical as targeted therapy with BRAF/MEK inhibitors significantly improves outcomes.
Gutierrez Amezcua JM, Arcila ME, Ng DL, Feratovic R, Bilal KH, Cohen JM, Wei XJ, Kezlarian-Sachs B, Sigel CS, Agaram N, Nafa K, Salazar P, Lin O, Kim D.   +13 more
europepmc   +2 more sources

Competence, specification and commitment in otic placode induction [PDF]

, 2000
The inner ear is induced from cranial ectoderm adjacent to the hindbrain. Despite almost a century of study, the molecular mechanisms of inner ear induction remain obscure. We have identified four genes expressed very early in the anlage of the inner ear,
Bronner-Fraser, Marianne, Groves, Andrew K.   +1 more
core  

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source