Results 141 to 150 of about 174,366 (328)

Netrin‐1 and B‐cell maturation antigen expression in a large cohort of 361 lymphomas: sensitive and specific staining in plasmablastic lymphomas, and therapeutic perspectives

open access: yesThe Journal of Pathology: Clinical Research
Netrin‐1 and B‐cell maturation antigen (BCMA) are currently being evaluated as therapeutic targets in oncology. However, studies investigating their expression in mature human lymphoid malignancies are sparse.
Marie Donzel   +9 more
doaj   +1 more source

Microfluidic single‐cell technologies for immunotherapeutic target discovery: From design concepts to preclinical applications

open access: yesVIEW, EarlyView.
Immunotherapy leverages the immune system to treat cancer and autoimmune diseases but is hindered by cellular heterogeneity in tissues and immune landscapes. Single‐cell technologies, particularly microfluidic‐enabled omics, revolutionize disease understanding by resolving this complexity at unprecedented resolution.
Haopu Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Diagnostic utility of immunocytochemistry by using liquid-based cytology (LBC) slides

open access: yesFolia Histochemica et Cytobiologica
INTRODUCTION: Cytological specimens, such as fine needle aspirations (FNAs) and exfoliative cytology samples, are minimally invasive options for diagnostic purposes.
Ozben Yalcin   +2 more
doaj   +1 more source

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. [PDF]

open access: yes, 2019
We generated cortical interneurons (cINs) from induced pluripotent stem cells derived from 14 healthy controls and 14 subjects with schizophrenia. Both healthy control cINs and schizophrenia cINs were authentic, fired spontaneously, received functional ...
Apud, Jose   +36 more
core   +1 more source

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Immunocytochemical localization of nitric oxide synthase-containing neurons in the visual cortex of the Mongolian gerbil

open access: yesFolia Histochemica et Cytobiologica
INTRODUCTION: Nitric oxide (NO) is present in various cell types in the central nervous system and plays a crucial role in the control of various cellular functions.
Xin-Yu Kuai   +2 more
doaj   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

open access: yesAndrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández   +9 more
wiley   +1 more source

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