Results 111 to 120 of about 468,207 (168)
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Hematology, 2003
AbstractHematological complications occur frequently in patients with both primary and secondary immunodeficiency disorders. Anemia, thrombocytopenia or leukopenias may bring these individuals to the attention of hematologists. Conversely, evidence suggesting a lymphoproliferative disorder may be the cause for referral.
Max D, Cooper +3 more
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AbstractHematological complications occur frequently in patients with both primary and secondary immunodeficiency disorders. Anemia, thrombocytopenia or leukopenias may bring these individuals to the attention of hematologists. Conversely, evidence suggesting a lymphoproliferative disorder may be the cause for referral.
Max D, Cooper +3 more
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Primary Care: Clinics in Office Practice, 2008
Primary immunodeficiencies are challenging in primary care settings, where clinicians often encounter patients with a history of recurrent infection. With advances in diagnostics and therapeutics, these disorders have been better understood and more successfully treated, yet their prognosis depends on early recognition of the disorder and initiation of
Yoshikazu, Morimoto, John M, Routes
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Primary immunodeficiencies are challenging in primary care settings, where clinicians often encounter patients with a history of recurrent infection. With advances in diagnostics and therapeutics, these disorders have been better understood and more successfully treated, yet their prognosis depends on early recognition of the disorder and initiation of
Yoshikazu, Morimoto, John M, Routes
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Immunomodulation and immunodeficiency
Veterinary Dermatology, 2004Abstract This article briefly reviews the concepts of immunodeficiency and immunomodulation as they relate to selected skin diseases in the dog and cat. Immunodeficiency states are uncommon and may be associated with a subnormal or down‐regulated immune system, including humoral deficiencies, such as IgA, and abnormal lymphocyte or neutrophil function.
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Autoimmunity and Immunodeficiency
Pediatrics In Review, 2015The references provided include data from evidence A and B studies based on the relevant populations. Because many primary immunodeficiencies associated with autoimmune diseases are rare, illustrative cases (evidence D) also are referenced. On the basis of level A evidence, immunoglobulin A deficiency is the most common primary immunodeficiency and is ...
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Autoimmunity and immunodeficiency
Current Opinion in Rheumatology, 2020Purpose of reviewAdvances in genomics and animal models of human disease have enabled the discovery of mechanisms important for host immunity and self-tolerance. Here, we summarize conceptual and clinical discoveries identified from 2018 to 2019 in the field of primary immunodeficiencies and autoimmunity.Recent findingsThree new primary ...
Rodrigo, Hoyos-Bachiloglu, Janet, Chou
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Immunodeficiency of the Elderly
Clinical Infectious Diseases, 1987The elderly are at risk for an increased incidence and severity of certain infections. The contribution of age-related immunologic impairment to the pathogenesis of these infections has been difficult to determine because of a number of confounding variables associated with aging.
R L, Saltzman, P K, Peterson
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Clinical Immunology and Immunopathology, 1986
Humoral (or antibody) immunodeficiency syndromes may occur as apparent congenital or acquired abnormalities, with deficiencies in all or in only some classes of immunoglobulins. Most patients are recognized because of recurrent infections with high-grade extracellular encapsulated bacterial pathogens, but some with selective IgA deficiency or with ...
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Humoral (or antibody) immunodeficiency syndromes may occur as apparent congenital or acquired abnormalities, with deficiencies in all or in only some classes of immunoglobulins. Most patients are recognized because of recurrent infections with high-grade extracellular encapsulated bacterial pathogens, but some with selective IgA deficiency or with ...
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Arthritis and immunodeficiency
The Journal of Pediatrics, 1972Summary A single case of chronic polyarthritis has been observed among 35 immunodeficient patients. Six additional patients have had transient arthritis or arthralgia, and two have had other musculoskeletal problems. This observation is not in accord with the high prevalence of chronic arthritis previously reported among immunodeficient patients. The
J F, McLaughlin +2 more
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Patients with Immunodeficiency
Medical Clinics of North America, 2013Patients presenting in an immunocompromised state merit special consideration when being evaluated for fitness to undergo surgery. A variety of immunodeficient conditions and their respective therapies, including human immunodeficiency virus, cancer, and transplantation, exert numerous systemic effects that may lead to multiorgan dysfunction ...
Michael J, Hannaman, Melissa J, Ertl
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Current Allergy and Asthma Reports, 2006
Primary immunodeficiency disorders (PIDs) continue to illuminate mechanisms of human immunity and hypersensitivity. New discoveries in common variable immunodeficiency, the most enigmatic of PID syndromes, reveal molecular pathways of importance in human antibody production. FOXP3 mutations demonstrate the essential role that T-regulatory cells play in
Michelle, Hernandez, John F, Bastian
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Primary immunodeficiency disorders (PIDs) continue to illuminate mechanisms of human immunity and hypersensitivity. New discoveries in common variable immunodeficiency, the most enigmatic of PID syndromes, reveal molecular pathways of importance in human antibody production. FOXP3 mutations demonstrate the essential role that T-regulatory cells play in
Michelle, Hernandez, John F, Bastian
openaire +2 more sources