Results 181 to 190 of about 881,591 (335)

Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection [PDF]

, 2017
Abdel-Mohsen, Akridge, Barr, Bishop, Cai, Cai, Campbell, Chaipan, Colomer-Lluch, Crowe, Daugherty, Ellery, Fitzpatrick, Gartner, Gaudin, Germinario, Giese, Ginhoux, Goldstone, Gonzalez-Scarano, Gosselin, Hammonds, Hancock, Hashimoto, Hassan, Hatch, Hoeffel, Honeycutt, Igarashi, Izquierdo-Useros, Jambo, Jaworowski, Jenkins, Jobe, Jobe, Kajaste-Rudnitski, Kedzierska, Kim, Koppensteiner, Koppensteiner, Krisko, Kuroda, Laguette, Lahouassa, Law, Li, Liu, Mlcochova, Montaner, Orenstein, Pertel, Phipson, Pino, Puryear, Ritchie, Rom, Rosa, Santa-Marta, Schmidt, Schnell, Sieweke, Sonza, St Gelais, Stabell, Swaminathan, Swingler, Tan, Turrini, Usami, Van Damme, Wang, Yan, Zou   +72 more
core   +2 more sources

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, EarlyView.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

Rapidly Progressive Disseminated Bacillus Calmette-Guérin Infection (BCGitis) in a 3-Month-Old Infant Without Immunodeficiency: A Case Report. [PDF]

Am J Case Rep
Perillo NQ, Heliodoro T, De Camargo LA, Gomes Avelino MA, Bahmad F.   +4 more
europepmc   +1 more source

The Great Impostor: Transaminitis Masking the Coinfection of Syphilis and Human Immunodeficiency Virus [PDF]

, 2017
Sunit Tolia, Hassan Kassem, Ana Capatina-Rata   +2 more
openalex   +1 more source

One‐Step Coaxial 3D Printing of Pre‐Vascularized Skin Organoid Models with ADSC Microspheres for Enhanced Wound Healing

Advanced Science, EarlyView.
A multifunctional vascular bed platform is created using coaxial 3D printing, allowing the one‐step integration of organoid microspheres with perfusable vascular structures. This strategy enables rapid and functional vascularization of organoids to support tissue repair and vascularization, providing a scalable and translationally promising approach ...
Kunrui Wang, Xiang Lan, Jianwei Chen, Yu Wu, Delong Zhu, Xiangkai Kong, Ying Hu, Qian Liu, Kun Wang, Tao Xu, Lei Zhu   +10 more
wiley   +1 more source

Griscelli syndrome type 2: A rare case report of pediatric immunodeficiency and neurological implications. [PDF]

Medicine (Baltimore)
Abubakir M, Abdul Rahman N, Hamza A, Haj Kasem S, Khayata MA, Kouja D.   +5 more
europepmc   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Primary Humoral Immunodeficiencies and Bronchiectasis in Adults. [PDF]

J Clin Med
Suárez-Cuartín G, Lores C, Gomez-Olivas JD, Oscullo G, Martínez-García MÁ.   +4 more
europepmc   +1 more source

Cumulative Mutations of Ubiquitin Acceptor Sites in Human Immunodeficiency Virus Type 1 Gag Cause a Late Budding Defect

, 2006
Eva Gottwein, Stefanie Jäger, Anja Habermann, Hans‐Georg Kräusslich   +3 more
openalex   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source