Results 251 to 260 of about 874,843 (291)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Griscelli syndrome type 2: A rare case report of pediatric immunodeficiency and neurological implications. [PDF]

Medicine (Baltimore)
Abubakir M, Abdul Rahman N, Hamza A, Haj Kasem S, Khayata MA, Kouja D.   +5 more
europepmc   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source

Immunodeficiency-Associated Childhood Interstitial Lung Diseases: Data from the Türkiye chILD Registry. [PDF]

Balkan Med J
Kekeç H, Şişmanlar Eyüboğlu T, Tana Aslan A, Medeni V, Zirek F, Tekin M, Gülen F, Güzelkaş İ, Eryılmaz Polat S, Kıykım A, Can Oksay S, Başaran AE, Ersoy A, Erdem Eralp E, Ünal G, Özsezen B, Kartal Öztürk G, Hangül M, Hızal M, Yılmaz Yeğit C, Nayır Büyükşahin H, Ünal F, Ramaslı Gürsoy T, Ayzıt Kılınç Sakallı A, Pekcan S, Çobanoğlu N, Cinel G, Gökdemir Y, Girit S, Yalçın E, Emiralioğlu N, Ceylan AC, Orhan D, Oğuz B, Kiper N.   +34 more
europepmc   +1 more source

Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants Resistant to Compounds that Inhibit Rev-RRE Function

, 2007
Deidra Shuck-Lee
openalex   +1 more source

A‐optimal model‐based design of experiments for processes with uncertain inputs

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Model‐based design of experiments (MBDoE) techniques are tools for selecting experimental conditions that enable accurate parameter estimation for mechanistic models. Most MBDoE approaches assume that the selected experimental conditions will be implemented perfectly, without uncertainties in the independent variables.
Bright Ofori, Iman Moshiritabrizi, Anh‐Duong Vo, Kimberley B. McAuley   +3 more
wiley   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Primary Humoral Immunodeficiencies and Bronchiectasis in Adults. [PDF]

J Clin Med
Suárez-Cuartín G, Lores C, Gomez-Olivas JD, Oscullo G, Martínez-García MÁ.   +4 more
europepmc   +1 more source

Effect of remobinant granulocyte-macrophage colony stimulating factor (GM-CSF) on leukopenia in AIDS [PDF]

, 1991
Bogner, Johannes R., Chatterjee, M., Ganser, A., Goebel, Frank-Detlef, Helm, E. B., Hoelzer, D., Ottmann, O. G., Seipelt, G.   +7 more
core  

Accelerating Generic Long‐Acting Antiretrovirals for Global HIV Treatment: Workshop Findings and a Roadmap to Access

Clinical Pharmacology &Therapeutics, EarlyView.
The global HIV response aims for widespread availability of affordable, quality‐assured long‐acting antiretroviral (LA ARV) drugs to achieve sustained epidemic control, particularly in low‐ and middle‐income countries. This report summarizes key discussion points, findings, and outcomes from an international workshop on generic LA ARVs, held in ...
Usman Arshad, Lobna Gaayeb, Henry Pertinez, Rajith K. R. Rajoli, Melynda Watkins, Parag Nimbolkar, Simone Perazzolo, Bharat Pagi, Annemarie Wensing, Saye Khoo, Marta Boffito, René Holm, Zack Panos, Imelda Mahaka, Francois Venter, Benny Kottiri, Keith W. Crawford, Rodney J. Y. Ho, Polly Clayden, Paul Domanico, Kimberly Struble, Andrew Owen, Charles Flexner   +22 more
wiley   +1 more source