Results 271 to 280 of about 1,114,238 (404)

Managing Primary Immunodeficiency Immunoglobulin Replacement Therapy-Related Adverse Events With Recombinant Human C1 Esterase Inhibitor Prophylaxis: A Case Report. [PDF]

Clin Case Rep
Jones DH, Memmott H.
europepmc   +1 more source

Active surveillance of drug safety in healthcare data: Sequential monitoring of bacterial and serious urinary tract infection risk in sodium‐glucose cotransporter 2 inhibitor users

British Journal of Clinical Pharmacology, EarlyView.
Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le, Dilsad Simay Peker, Lukas Frederic Westphal, Nikolai Brun, Christine Erikstrup Hallgreen, Morten Andersen   +5 more
wiley   +1 more source

Upregulation of interferon-γ activation in patients with anti-interferon-γ autoantibodies immunodeficiency syndrome: insights from single-cell analysis. [PDF]

Front Immunol
Liang SQ, Huang XM, Liang XN, Wu SY, Hong LM, Chen N, Luo ZT, Ning Y, Wang MC, He ZY.   +9 more
europepmc   +1 more source

Active human immunodeficiency virus protease is required for viral infectivity.

Proceedings of the National Academy of Sciences of the United States of America, 1988
N. Kohl, E. Emini, W. Schleif, L. Davis, J. C. Heimbach, R. A. Dixon, E. Scolnick, I. Sigal   +7 more
semanticscholar   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Human immunodeficiency virus reverse transcriptase and protease sequence database

Nucleic Acids Res., 2003
Soo-Yon Rhee, M. J. Gonzales, R. Kantor, B. Betts, Jaideep Ravela, R. Shafer   +5 more
semanticscholar   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Analysis of macular microvasculature changes in human immunodeficiency virus infection using swept-source OCT angiography. [PDF]

BMC Ophthalmol
Doukh M, Ghorbel M, Abid M, Bedhiafi A, Omezzine Letaief A.   +4 more
europepmc   +1 more source

Transplantation outcomes for severe combined immunodeficiency, 2000-2009.

New England Journal of Medicine, 2014
S. Pai, B. Logan, Linda M Griffith, R. Buckley, R. Parrott, C. Dvorak, N. Kapoor, I. C. Hanson, A. Filipovich, S. Jyonouchi, K. Sullivan, T. Small, L. Burroughs, S. Skoda-Smith, A. Haight, A. Grizzle, M. Pulsipher, K. Chan, R. Fuleihan, E. Haddad, B. Loechelt, V. Aquino, A. Gillio, Jeffrey H Davis, A. Knutsen, Angela R. Smith, T. Moore, M. Schroeder, F. Goldman, J. Connelly, M. Porteus, Q. Xiang, W. Shearer, T. Fleisher, D. Kohn, J. Puck, L. Notarangelo, M. Cowan, R. O'reilly   +38 more
semanticscholar   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source