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Pediatrics In Review, 1993
Introduction Immunodeficiency diseases are a group of disorders that increase susceptibility to infection, malignancy, and autoimmunity. Deficiencies of the immune system may be congenital or acquired. They may be secondary to a developmental anomaly or an enzymatic defect or be of unknown etiology.
M, Iseki, D C, Heiner
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Introduction Immunodeficiency diseases are a group of disorders that increase susceptibility to infection, malignancy, and autoimmunity. Deficiencies of the immune system may be congenital or acquired. They may be secondary to a developmental anomaly or an enzymatic defect or be of unknown etiology.
M, Iseki, D C, Heiner
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IMMUNODEFICIENCY AND IMMUNOBIOLOGY
Pediatrics, 1971Almost 20 years ago in this journal, Bruton1 described a young boy afflicted with recurrent severe infections, who lacked gamma globulin. His description identified a new disease and heralded a new era in immunobiology. "Agammaglobulinemia," the term he coined, described a condition of immunodeficiency in a manner analogous to the use of the term ...
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Patients with Immunodeficiency
Medical Clinics of North America, 2013Patients presenting in an immunocompromised state merit special consideration when being evaluated for fitness to undergo surgery. A variety of immunodeficient conditions and their respective therapies, including human immunodeficiency virus, cancer, and transplantation, exert numerous systemic effects that may lead to multiorgan dysfunction ...
Michael J, Hannaman, Melissa J, Ertl
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Current Allergy and Asthma Reports, 2006
Primary immunodeficiency disorders (PIDs) continue to illuminate mechanisms of human immunity and hypersensitivity. New discoveries in common variable immunodeficiency, the most enigmatic of PID syndromes, reveal molecular pathways of importance in human antibody production. FOXP3 mutations demonstrate the essential role that T-regulatory cells play in
Michelle, Hernandez, John F, Bastian
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Primary immunodeficiency disorders (PIDs) continue to illuminate mechanisms of human immunity and hypersensitivity. New discoveries in common variable immunodeficiency, the most enigmatic of PID syndromes, reveal molecular pathways of importance in human antibody production. FOXP3 mutations demonstrate the essential role that T-regulatory cells play in
Michelle, Hernandez, John F, Bastian
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Autoimmunity and immunodeficiency
Current Opinion in Rheumatology, 2020Purpose of reviewAdvances in genomics and animal models of human disease have enabled the discovery of mechanisms important for host immunity and self-tolerance. Here, we summarize conceptual and clinical discoveries identified from 2018 to 2019 in the field of primary immunodeficiencies and autoimmunity.Recent findingsThree new primary ...
Rodrigo, Hoyos-Bachiloglu, Janet, Chou
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Hematology, 2003
AbstractHematological complications occur frequently in patients with both primary and secondary immunodeficiency disorders. Anemia, thrombocytopenia or leukopenias may bring these individuals to the attention of hematologists. Conversely, evidence suggesting a lymphoproliferative disorder may be the cause for referral.
Max D, Cooper +3 more
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AbstractHematological complications occur frequently in patients with both primary and secondary immunodeficiency disorders. Anemia, thrombocytopenia or leukopenias may bring these individuals to the attention of hematologists. Conversely, evidence suggesting a lymphoproliferative disorder may be the cause for referral.
Max D, Cooper +3 more
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Primary Care: Clinics in Office Practice, 2008
Primary immunodeficiencies are challenging in primary care settings, where clinicians often encounter patients with a history of recurrent infection. With advances in diagnostics and therapeutics, these disorders have been better understood and more successfully treated, yet their prognosis depends on early recognition of the disorder and initiation of
Yoshikazu, Morimoto, John M, Routes
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Primary immunodeficiencies are challenging in primary care settings, where clinicians often encounter patients with a history of recurrent infection. With advances in diagnostics and therapeutics, these disorders have been better understood and more successfully treated, yet their prognosis depends on early recognition of the disorder and initiation of
Yoshikazu, Morimoto, John M, Routes
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Clinical Immunology and Immunopathology, 1986
Humoral (or antibody) immunodeficiency syndromes may occur as apparent congenital or acquired abnormalities, with deficiencies in all or in only some classes of immunoglobulins. Most patients are recognized because of recurrent infections with high-grade extracellular encapsulated bacterial pathogens, but some with selective IgA deficiency or with ...
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Humoral (or antibody) immunodeficiency syndromes may occur as apparent congenital or acquired abnormalities, with deficiencies in all or in only some classes of immunoglobulins. Most patients are recognized because of recurrent infections with high-grade extracellular encapsulated bacterial pathogens, but some with selective IgA deficiency or with ...
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Annals of Internal Medicine, 1972
Excerpt Information on the nature and variety of immunodeficiency states has accumulated rapidly in recent years.
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Excerpt Information on the nature and variety of immunodeficiency states has accumulated rapidly in recent years.
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Veterinary Clinics of North America: Equine Practice
Knowledge of immunodeficiencies is crucial to neonatal medicine, in that they predispose to sepsis in the newborn and neonatal foal, as well as recurrent infections in older foals. The most common immunodeficiency in newborn and neonatal foals is failure of passive transfer, which is an example of an acquired immunodeficiency.
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Knowledge of immunodeficiencies is crucial to neonatal medicine, in that they predispose to sepsis in the newborn and neonatal foal, as well as recurrent infections in older foals. The most common immunodeficiency in newborn and neonatal foals is failure of passive transfer, which is an example of an acquired immunodeficiency.
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