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Journal of Clinical Pathology, 2008 T cell immunodeficiency can occur as one of a group of primary disorders or develop secondary to chronic infection, illness or drug therapy. Primary T cell disorders are rare, accounting for approximately 11% of reported primary immunodeficiencies, and generally present in infancy or early childhood. Early recognition is very important as many of these
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Autoimmunity and Immunodeficiency
Pediatrics In Review, 2015The references provided include data from evidence A and B studies based on the relevant populations. Because many primary immunodeficiencies associated with autoimmune diseases are rare, illustrative cases (evidence D) also are referenced. On the basis of level A evidence, immunoglobulin A deficiency is the most common primary immunodeficiency and is ...
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Current Allergy and Asthma Reports, 2006
Primary immunodeficiency disorders (PIDs) continue to illuminate mechanisms of human immunity and hypersensitivity. New discoveries in common variable immunodeficiency, the most enigmatic of PID syndromes, reveal molecular pathways of importance in human antibody production. FOXP3 mutations demonstrate the essential role that T-regulatory cells play in
John F. Bastian, Michelle Hernandez
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Primary immunodeficiency disorders (PIDs) continue to illuminate mechanisms of human immunity and hypersensitivity. New discoveries in common variable immunodeficiency, the most enigmatic of PID syndromes, reveal molecular pathways of importance in human antibody production. FOXP3 mutations demonstrate the essential role that T-regulatory cells play in
John F. Bastian, Michelle Hernandez
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2004
Abstract If there were people who had never thought much about immunodeficiency, or indeed about immunity at all, the AIDS epidemic must have opened their eyes. For immunologists, it was a nightmare come true. Here as we watched, fascinated and horrified, was the proof of all the things we had been teaching our rather bored students for ...
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Abstract If there were people who had never thought much about immunodeficiency, or indeed about immunity at all, the AIDS epidemic must have opened their eyes. For immunologists, it was a nightmare come true. Here as we watched, fascinated and horrified, was the proof of all the things we had been teaching our rather bored students for ...
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1973
Publisher Summary This chapter presents evidence indicating a relationship between the immunologic system and malignancy arose partially from a hypothesis presented by Thomas (1959). This hypothesis suggested that a major role of the immune system (and especially the cell-mediated system) may be in the host defense against malignant cells.
Beatrice D. Spector +2 more
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Publisher Summary This chapter presents evidence indicating a relationship between the immunologic system and malignancy arose partially from a hypothesis presented by Thomas (1959). This hypothesis suggested that a major role of the immune system (and especially the cell-mediated system) may be in the host defense against malignant cells.
Beatrice D. Spector +2 more
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Annals of Internal Medicine, 1972
Excerpt Information on the nature and variety of immunodeficiency states has accumulated rapidly in recent years.
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Excerpt Information on the nature and variety of immunodeficiency states has accumulated rapidly in recent years.
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The New Zealand medical journal, 2004
Thymoma and ...
DI RENZO, MICHELA +6 more
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Thymoma and ...
DI RENZO, MICHELA +6 more
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Pediatric Clinics of North America, 2000
T-cell immune defects include most inherited immunodeficiencies diagnosed in childhood. Most cellular immunodeficiencies have associated humoral defects with variable clinical and laboratory features. The underlying gene defects are now known for most inherited T-cell immune defects, and mutation analysis is quickly becoming an integral part of ...
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T-cell immune defects include most inherited immunodeficiencies diagnosed in childhood. Most cellular immunodeficiencies have associated humoral defects with variable clinical and laboratory features. The underlying gene defects are now known for most inherited T-cell immune defects, and mutation analysis is quickly becoming an integral part of ...
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