Results 331 to 340 of about 1,052,494 (379)

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Durvalumab-associated membranous nephropathy: a case report and brief literature review. [PDF]

CEN Case Rep
Mizoguchi R, Tashiro T, Sakakima M.
europepmc   +1 more source

A Rare Type of Bullous Disorder in a Child. Can It Be Chronic Bullous Disease of Childhood? [PDF]

Clin Case Rep
Yadav R, Poudel I, Poudyal Y, Chaudhary N.   +3 more
europepmc   +1 more source

A Rare Case of Dupilumab Monotherapy in Pemphigoid Nodularis and a Comprehensive Literature Review. [PDF]

Cureus
Albthali SM, Alajmi FM, Almutairi S, Al-Sabah H.   +3 more
europepmc   +1 more source

Dynamic crosstalk between Tspan4⁺ macrophage subsets and MSCs via migrasomes orchestrates fracture repair. [PDF]

Front Cell Dev Biol
Zhang S, Wang M, Kutibiding A, Liu D, Manafu T, Zhao W, Yang Y.   +6 more
europepmc   +1 more source

Enhancement of Hypoxia-Induced Autophagy via the HIF-1apha/BNIP3 Pathway Promotes Proliferation and Myogenic Differentiation of Aged Skeletal Muscle Satellite Cells. [PDF]

Life (Basel)
Zhou L, Feng C, Lin J, Geng M, Qu D, Xing J, Lin H, Ma X, Nakanishi R, Maeshige N, Kondo H, Fujino H.   +11 more
europepmc   +1 more source

BvrR From Brucella abortus Induces Neuroinflammation Through IRE1-Mediated Activation of ATF2 and NF-κB. [PDF]

Microbiologyopen
Wang Z, Yu X, Liu B, Ren D.
europepmc   +1 more source

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Immunohistochemistry and Immunofluorescence

Methods in molecular biology, 2022
Immunohistochemistry (IHC) is one of the most widely used protein detection techniques. The principle of this technique is based on the binding of a specific antibody to a matching specific antigen in tissue. The bound antigen-antibody complex then is visualized using a range of detection techniques.
Haizal Mohd, Hussaini, Benedict, Seo, Alison M, Rich   +2 more
openaire   +3 more sources

Practical Direct Immunofluorescence

The American Journal of Dermatopathology, 2020
Abstract: Direct immunofluorescence (DIF) remains a valuable tool that may be underused because of perceived challenges in the interpretation, limitations, and processing of DIF specimens. The aim of this review is to provide a practical guide for appropriately incorporating DIF in a variety of clinical diseases, such as autoimmune blistering
Randie H, Kim, Nooshin K, Brinster
openaire   +3 more sources

Multiplex Immunofluorescence Assays

Methods in molecular biology, 2019
Multiplexed imaging platforms to simultaneously detect multiple epitopes in the same tissue section emerged in the last years as very powerful tools to study tumor immune contexture. These revolutionary technologies are providing a deep methodology for tumor evaluation in formalin-fixed and paraffin-embedded (FFPE) to improve the understanding of tumor
Alejandro, Francisco-Cruz, Edwin Roger, Parra, Michael T, Tetzlaff, Ignacio I, Wistuba   +3 more
openaire   +3 more sources