Immunogenicity of Trinitrophenyl-Hemocyanin: Production of Primary and Secondary Anti-Hapten Precipitins [PDF]
, 1966 Marvin B. Rittenberg, Alfred A. Amkraut
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Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
MEK inhibition and immune responses in advanced melanoma
OncoImmunology, 2017 phase II and III clinical trials demonstrated modest anti- tumor activity of Binimetinib (MEK162) - a potent allosteric inhibitor of MEK1 and MEK2- in patients with advanced NRAS mutant melanoma.
Reinhard Dummer +5 more
doaj +1 more source
Preparation of Highly Immunogenic Ribosomal Fractions ofMycobacterium tuberculosisby Use of Sodium Dodecyl Sulfate [PDF]
, 1966 Anne S. Youmans, Guy P. Youmans
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Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, EarlyView.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
NATURE OF THE LABILE IMMUNOGENIC SUBSTANCE IN THE PARTICULATE FRACTION ISOLATED FROMMYCOBACTERIUM TUBERCULOSIS [PDF]
, 1964 Anne S. Youmans, Guy P. Youmans
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Advanced Healthcare Materials, EarlyView.A shrinkage‐resistant hydrogel is developed to confer post‐fabrication shape fidelity. The hydrogel, based on recombinant spider silk protein eADF4(C16)‐RGD and collagen‐I, exhibits tunable mechanical properties and shrink‐resistance in the presence of fibroblasts as well as muscle cells.
Xuen J. Ng +10 more
wiley +1 more source
Virulence and Immunogenicity in Mice of Airborne Encephalomyocarditis Viruses and Their Infectious Nucleic Acids [PDF]
, 1966 Thomas G. Akers +3 more
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Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
The Immunogenicity of Hapten-Polylysine Conjugates [PDF]
, 1965 Christopher Parker +2 more
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