Results 201 to 210 of about 315,728 (345)

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

Impact of systemic anticancer therapy timing on cancer vaccine immunogenicity: a review. [PDF]

Ther Adv Med Oncol
Gomez-Randulfe I, Lavender H, Symeonides S, Blackhall F.   +3 more
europepmc   +1 more source

The antigenicity and immunogenicity of cell-free extracts of chemically induced murine sarcomas

, 1969
Yosef H. Pilch
openalex   +1 more source

Polyplex Nanomicelle‐Mediated Pgc‐1α4 mRNA Delivery Via Hydrodynamic Limb Vein Injection Enhances Damage Resistance in Duchenne Muscular Dystrophy Mice

Advanced Science, EarlyView.
This study presents a novel approach for treating Duchenne muscular dystrophy using mRNA encoding PGC‐1α4. Nanomicelle‐delivered Pgc‐1α4 mRNA enhances muscle damage resistance and mitochondrial activity in dystrophic muscles. This study demonstrates the potential of mRNA therapy for neuromuscular diseases like Duchenne muscular dystrophy and highlights
Xuan Du, Hideyuki Nakanishi, Takashi Yamada, Yooksil Sin, Katsura Minegishi, Norio Motohashi, Yoshitsugu Aoki, Keiji Itaka   +7 more
wiley   +1 more source

Antigenic and Immunogenic Studies on Purified Tetanus Toxoid [PDF]

, 1967
Peter Aadal Nielsen, Frank B. Ablondi, MERLE V. QUERRY, Cecilia Gussoni, Mark S. Cooper   +4 more
openalex   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

TumorAgDB1.0: tumor neoantigen database platform. [PDF]

Database (Oxford)
Shao Y, Gao Y, Wu LY, Ge SG, Wen PB.
europepmc   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Immunogenicity and Safety of the Higher-Valent Pneumococcal Conjugate Vaccine vs the 13-Valent Pneumococcal Conjugate Vaccine in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. [PDF]

Open Forum Infect Dis
Ngamprasertchai T, Ruenroengbun N, Kajeekul R.   +2 more
europepmc   +1 more source

Osteosarcoma Cell‐Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis

Advanced Science, EarlyView.
Migrasomes are newly discovered organelles in migrating cells. This study finds that osteosarcoma cell‐derived migrasomes promote the tumor‐promoting phenotype of macrophages and further aggravate osteosarcoma malignant progression via milk fat globule‐EGF factor 8.
Wanshun Liu, Lei Li, Xiaoming Bai, Mengxue Zhang, Wei Lv, Yongbin Ma, Yuzhi Sun, Hongjing Zhang, Qing Jiang, Qingqiang Yao, Zhi‐Yuan Zhang   +10 more
wiley   +1 more source