Results 211 to 220 of about 364,936 (336)

Mass spectrometric identification of immunogenic SARS-CoV-2 epitopes and cognate TCRs

, 2021
Ke Pan, Yulun Chiu, Eric Huang, Michelle Chen, Junmei Wang, Ivy Lai, Shailbala Singh, Rebecca Shaw, Michael J. MacCoss, Cassian Yee   +9 more
openalex   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Mucosal immunization of piglets with purified F18 fimbriae does not protect against F18(+) Escherichia coli infection [PDF]

, 2007
CLEMENTSD, J, Cox, Eric, Goddeeris, Bruno, LYCKE, N, Tiels, Petra, VAN GOG, K, Verdonck, Frank   +6 more
core   +1 more source

Clinical Pharmacology Perspective on Direct-To-Subcutaneous Dosing of T Cell Engagers in Oncology First-In-Human Studies. [PDF]

Clin Transl Sci
Qiao W, Shahraz A, Vishwanathan K, Sawant-Basak A.   +3 more
europepmc   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Sex Differences in Response to Viral Vector Vaccines-Implications for Future Vaccine Design. [PDF]

Immunol Rev
Grewe I, Zoran T, Addo MM.
europepmc   +1 more source

Carboxyl-terminal domain of the Epstein-Barr virus nuclear antigen is highly immunogenic in man.

, 1985
Gregory Milman, Alan L. Scott, M S Cho, Steven Hartman, D. K. Ades, Gary S. Hayward, Potrashkova Ki, J. T. August, S. Diane Hayward   +8 more
openalex   +2 more sources

Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity [PDF]

, 2017
Regina Salvat, Deeptak Verma, Andrew S. Parker, Jack R. Kirsch, Seth A. Brooks, Chris Bailey‐Kellogg, Karl E. Griswold   +6 more
openalex   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors [PDF]

, 2015
Ronit Mazor, Jingli Zhang, Laiman Xiang, Selamawit Addissie, Prince Awuah, Richard Beers, Raffit Hassan, Ira Pastan   +7 more
openalex   +1 more source