Results 241 to 250 of about 350,984 (342)

A real-time imaging approach to quantify dendritic cell internalization for immunogenicity risk assessment of biotherapeutics. [PDF]

Front Immunol
Yin Z, Tran P, Guerrero J, Low J, Xie Q, Peng K.   +5 more
europepmc   +1 more source

Immunogenicity of Plague Vaccines in Mice and Guinea Pigs [PDF]

, 1971
Eleanor Von Metz, Daniel M. Eisler, G. A. Hottle   +2 more
openalex   +1 more source

Gallium β‐Cyclodextrin Nanoparticles Containing both Gallium Protoporphyrin and Gallium Nitrate Exhibit Antimicrobial Activity against Nontuberculous Mycobacteria in Vitro and in Vivo

Advanced Therapeutics, EarlyView.
Cyclodextrin nanoparticle containing both Ga(NO3)3 and GaPP is synthesized and tested against non‐tuberculous mycobacteria (NTM). The in vivo efficacy of the nanoparticle therapy is additionally tested by treating pulmonary NTM infections in mice and observed much greater effectiveness in bacterial clearance and survival of mice.
Seoung‐ryoung Choi, Bradley E. Britigan, Prabagaran Narayanasamy   +2 more
wiley   +1 more source

Safety and immunogenicity of rVSVΔG-ZEBOV-GP vaccination when dosed concurrent with mRNA COVID-19 vaccine booster doses in healthy African adults (EbolaCov): protocol for a phase IV, single-centre, single-blinded, randomised controlled trial. [PDF]

BMJ Open
Gokani K, Taylor A, Packham A, Musabyimana JP, Shema H, Mutabaruka A, Roche S, Takwoingi Y, Umuhoza C, Nyombayire J, Muvunyi C, Green C.   +11 more
europepmc   +1 more source

Immunogenicity of Liposomal Model Membranes Sensitized with Dinitrophenylated Phosphatidylethanolamine Derivatives Containing Different Length Spacers [PDF]

, 1979
George F. Dancey, Peter C. Isakson, Stephen C. Kinsky   +2 more
openalex   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

The antigenicity and immunogenicity of cell-free extracts of chemically induced murine sarcomas

, 1969
Yosef H. Pilch
openalex   +1 more source

Effect of Lipopolysaccharide on Immunogenicity and Tolerogenicity of HGG in C57BL/6J Nude Mice: Evidence for a Possible B Cell Deficiency [PDF]

, 1977
D E Parks, Michael Doyle, William O. Weigle   +2 more
openalex   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Analytical Data and Single-Dose PK are Sufficient to Conclude Comparable Immunogenicity for Biosimilars: An Ustekinumab Case Study. [PDF]

BioDrugs
Schiestl M, Roy N, Trieb M, Park JP, Guillen E, Woollett G, Wolff-Holz E.   +6 more
europepmc   +1 more source