Results 251 to 260 of about 315,728 (345)

Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS‐Induced Depressive‐Like Behaviors

Advanced Science, EarlyView.
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao, Zhongkun Zhang, Minzi Ju, Liang Bian, Huijuan Wang, Sibo Zhao, Ningbo Cai, Yu Wang, Yanpeng Jia, Ling Shen, Yuan Zhang, Honghong Yao   +11 more
wiley   +1 more source

IMMUNOGENICITY IN MONKEYS OF A COMBINED TOXOID FROM THE MAIN TOXIC PRINCIPLES SEPARATED FROM HABU SNAKE VENOM

, 1970
Hisashi Kondo, Seiji Sadahiro, Satoru Kondo, KIYOSUMI YAMAUCHI, Shigeo Honjo, Fumiaki Cho, Akira Ohsaka, Ryosuke Murata   +7 more
openalex   +2 more sources

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

Advanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan, Qing Pei, Haojie Sun, Haiyan Zhang, Zhigang Xie, Tao Zhang, Chong Ma   +6 more
wiley   +1 more source

Anti-Drug Antibody Response to Therapeutic Antibodies and Potential Mitigation Strategies. [PDF]

Biomedicines
Howard EL, Goens MM, Susta L, Patel A, Wootton SK.   +4 more
europepmc   +1 more source

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

Cell, 2016
T. Vatanen, A. Kostic, Eva d’Hennezel, Heli Siljander, E. Franzosa, M. Yassour, R. Kolde, H. Vlamakis, Timothy D. Arthur, A. Hämäläinen, A. Peet, V. Tillmann, R. Uibo, Sergei Mokurov, N. Dorshakova, J. Ilonen, S. Virtanen, S. Szabo, Jeffrey A. Porter, H. Lähdesmäki, C. Huttenhower, D. Gevers, T. W. Cullen, M. Knip, R. Xavier   +24 more
semanticscholar   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo.

Molecules and Cells, 2019
R. A. Wesselhoeft, Piotr S. Kowalski, Frances C Parker-Hale, Yuxuan, Huang, Namita Bisaria, Daniel G. Anderson   +6 more
semanticscholar   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

A Meta-Analysis on the Immunogenicity of Homologous versus Heterologous Immunization Regimens against SARS-CoV-2 Beta, Delta, and Omicron BA.1 VoCs in Healthy Adults. [PDF]

J Microbiol Biotechnol
Ndzouboukou JB, Kamara AA, Ullah N, Lei Q, Fan XL.   +4 more
europepmc   +1 more source

Tetanus toxin. The effect of chemical modifications on toxicity, immunogenicity, and conformation.

, 1975
John P. Robinson, John B. Picklesimer, David Puett   +2 more
openalex   +1 more source