Results 21 to 30 of about 267,464 (292)

Immunogenicity of allogeneic mouse mesenchymal stem cells (MSC) [PDF]

open access: yes, 2012
Adult mesenchymal stem cells (MSC) are multipotential cells which can differentiate into various cell types thus giving them utility in tissue engineering regenerative medicine and cell-based therapies.
Mukonoweshuro, Blessing
core   +5 more sources

German experimental hepatitis B vaccine: influence of variation of dosage schedule, sex and age differences on immunogenicity in health care workers [PDF]

open access: yes, 1986
Krämer A, Sommer D, Hahn EG, Riecken E-O. German experimental hepatitis B vaccine: influence of variation of dosage schedule, sex and age differences on immunogenicity in health care workers. Klinische Wochenschrift.
Sommer, D.   +7 more
core   +1 more source

Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study [PDF]

open access: yes, 2010
Objectives: To compare the safety, reactogenicity, and immunogenicity of an adjuvanted split virion H1N1 vaccine and a non-adjuvanted whole virion vaccine used in the pandemic immunisation programme in the United Kingdom.
Sheasby, E   +52 more
core   +1 more source

Immunogenicity profile.

open access: yes, 2022
Immunogenicity profile.
Andrey L. Bakulev (5727509)   +14 more
core   +1 more source

Safety and immunogenicity of H1/IC31®, an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ lymphocyte counts greater than 350 cells/mm3: a phase II, multi-centre, double-blind, randomized, placebo-controlled trial. [PDF]

open access: yes, 2014
BACKGROUND: Novel tuberculosis vaccines should be safe, immunogenic, and effective in various population groups, including HIV-infected individuals. In this phase II multi-centre, double-blind, placebo-controlled trial, the safety and immunogenicity of ...
Said, Khadija   +107 more
core   +1 more source

Understanding the Supersensitive Anti-Drug Antibody Assay: Unexpected High Anti-Drug Antibody Incidence and Its Clinical Relevance

open access: yesJournal of Immunology Research, 2016
Numbers of biotherapeutic products in development have increased over past decade. Despite providing significant benefits to patients with unmet needs, almost all protein-based biotherapeutics could induce unwanted immunogenicity, which result in a loss ...
Sam Song   +3 more
doaj   +1 more source

Learn–confirm in model‐informed drug development: Assessing an immunogenicity quantitative systems pharmacology platform

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2023
Immunogenicity against therapeutic proteins frequently causes attrition owing to its potential impact on pharmacokinetics, pharmacodynamics, efficacy, and safety.
Linnea C. Franssen   +5 more
doaj   +1 more source

A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children. [PDF]

open access: yes, 2010
BACKGROUND: The emergence of drug resistant typhoid fever is a major public health problem, especially in Asia. An oral single dose typhoid vaccine would have major advantages.
Schultsz, C   +150 more
core   +1 more source

Trastuzumab immunogenicity development in patients’ sera and in laboratory animals

open access: yesBMC Immunology, 2021
Background Immunogenicity is a major challenge in drug development and patient care. Clinicians and regulators are familiar with immunogenicity concerns of monoclonal antibody (mAb) therapeutics, growth factors and enzyme replacements.
Lobna Abdel Aziz Kilany   +3 more
doaj   +1 more source

Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: Different boosting intervals and implications for efficacy trials [PDF]

open access: yes, 2007
Objectives. To investigate the safety and immunogenicity of boosting BCG with modified vaccinia Ankara expressing antigen 85A (MVA85A), shortly after BCG vaccination, and to compare this first with the immunogenicity of BCG vaccination alone and second
Whelan, KT   +35 more
core   +1 more source

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