Results 41 to 50 of about 19,572,353 (382)

Targeted therapy in severe asthma today: focus on immunoglobulin E

open access: yesDrug Design, Development and Therapy, 2017
Asthma is a complex chronic inflammatory disease of multifactorial etiology. International guidelines increasingly recognize that a standard “one size fits all” approach is no longer an effective approach to achieve optimal treatment outcomes, and a ...
G. Pelaia   +5 more
semanticscholar   +1 more source

A Multi-Center Study of the Prevalence and Characteristics of Eosinophilic Phenotype and High IgE Levels Among Chinese Patients with Severe Asthma

open access: yesJournal of Asthma and Allergy, 2023
Fanny Wai-San Ko,1 Julie KL Wang,2 David SC Hui,1 Johnny WM Chan,3 Pik-Shan Cheung,4 Yiu-Cheong Yeung,5 Kit Man Sin,6 Mary Sau-Man Ip7 1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People’s Republic of China ...
Ko FWS   +7 more
doaj  

Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women [PDF]

open access: yesDiabetes & Metabolism Journal, 2021
Background Although studies have shown that obesity is associated with aeroallergen sensitization (atopy), controversy still exists. We aimed to investigate the association between metabolic status, obesity, and atopy stratified by sex and menopausal ...
Seung Eun Lee   +3 more
doaj   +1 more source

Subcutaneous IgG Replacement Therapy by Push in 32 Patients with Primary Immunodeficiency Diseases in Argentine [PDF]

open access: yes, 2014
Introduction: Regular replacement with immunoglobulin infusions is the mainstay of treatment in the majority of primary immunodeficiencies. Several studies showed that Subcutaneous Immunoglobulin (SCIG) has similar efficacy to Intravenous Immunoglobulin (
Bezrodnik, Liliana   +6 more
core   +1 more source

Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]

open access: yes, 2016
Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht   +13 more
core   +1 more source

Kimura disease: A rare presentation in the rheumatology clinic

open access: yesIndian Journal of Rheumatology, 2020
Kimura disease (KD) is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling in head and neck region, accompanied by regional lymphadenopathy and ...
Malay Kumar   +4 more
doaj   +1 more source

Local Immunoglobulin E in the Nasal Mucosa: Clinical Implications

open access: yesAllergy Asthma and Immunology Research, 2015
Immunoglobulin E (IgE) can be highly elevated in the airway mucosa independently of IgE serum levels and atopic status. Mostly, systemic markers are assessed to investigate inflammation in airway disease for research or clinical practice. A more accurate
E. De Schryver   +6 more
semanticscholar   +1 more source

Angioedema-post COVID symptoms

open access: yesAIMS Allergy and Immunology, 2023
The non-respiratory symptoms associated with coronavirus disease 2019 (COVID-19) are being reported more frequently as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads throughout the world. Numerous dermatological issues have been
Swathi Mukurala   +2 more
doaj   +1 more source

Siglec receptors impact mammalian lifespan by modulating oxidative stress. [PDF]

open access: yes, 2015
Aging is a multifactorial process that includes the lifelong accumulation of molecular damage, leading to age-related frailty, disability and disease, and eventually death. In this study, we report evidence of a significant correlation between the number
Fu, Xiaoming   +16 more
core   +1 more source

Dupilumab Treatment Efficacy and Impact on Clinical Scores, Serum Biomarkers, and Itch in Adult Patients with Atopic Dermatitis: A Retrospective Analysis

open access: yesJournal of Asthma and Allergy, 2023
Mariateresa Rossi,* Luca Bettolini,* Grazia Linda Artelli, Alessandro Fraghì, Cesare Tomasi, Piergiacomo Calzavara-Pinton Dermatology Department, University of Brescia, ASST Spedali Civili di Brescia, Brescia, Italy*These authors contributed ...
Rossi M   +5 more
doaj  

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