Clinical usefulness of anti-α3Gal immunoglobulin E assays for cetuximab-mediated anaphylaxis in head and neck cancer. [PDF]
Immunooncol TechnolPointreau Y +5 more
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Development and preclinical characterization of AMG 329: a human antibody neutralizing FLT3 ligand. [PDF]
MAbsLau-Kilby A +14 more
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Discovery and Characterization of Unusual O-Linked Glycosylation of IgG4 Antibody Using LC-MS. [PDF]
Rapid Commun Mass SpectromJanecki DJ, Kao-Scharf CY, Hoffmann A.
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Use of molecular replacement in the solution of an immunoglobulin Fab fragment structure [PDF]
Acta Crystallographica Section B Structural Science, 1991 Molecular-replacement efficiency depends highly on structural and sequence homologies between available models and the molecule in the crystal being studied. The structure of the Fab fragment of an antibody specific for an influenza virus hemagglutinin was determined by molecular replacement and the Fv and the CH1:CL parts were localized separately ...
Y. Mauguen +3 more
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Crystallographic Data for the Fab Fragment of a Human Myeloma Immunoglobulin
Nature, 1968COMPARISONS of the physical properties and chemical structure of myeloma proteins with those of other immunoglobulins and antibodies have indicated that myeloma proteins are abnormal only in their relative homogeneity; they seem to be typical representatives of the immunoglobulin class to which they belong. In addition, antibody activity has been shown
AVEY H. P +3 more
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The Alternative Binding Site for Protein A in the Fab Fragment of Immunoglobulins
Scandinavian Journal of Immunology, 1993Twenty‐six new human or murine monoclonal immunoglobulins (IgM, IgA, murine IgGl or human IgG3) with a known V‐region sequence were tested for alternative (non‐Fc) binding to Staphylococcal protein A. Seven of them did not bind at all. Four immunoglobulins (all mouse IgGl) were bound but easily eluted (at pH 6). They were probably bound via the Fc part.
Matti Kaartinen +4 more
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Allotypic markers on Fab fragments of mouse immunoglobulins.
Journal of immunology (Baltimore, Md. : 1950), 1974Abstract Allotypic determinants were detected on the Fab fragments of mouse IgG by guinea pig antisera prepared against polymerized Fab fragments of IgG from the C57BL and AKR strains. Different markers were detected by the two antisera. Indirect precipitation, with 125I-labeled Fab as ligand, was used for the assay.
Spring, S B, Nisonoff, A
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Chemical characterisation of the Fab and Fc fragments from surface immunoglobulin
Nature, 1980Immunoglobulin (Ig) molecules of the M and D classes are present on the membranes of B lymphocytes (sIg), where they serve as antigen receptors1–6. sIg is a biosynthetically stable membrane protein which requires either denaturing conditions or detergents to free it from other membrane constituents1,7–9.
John Lifter +2 more
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An EM study of phosphorylcholine-binding Fab′ immunoglobulin fragment crystals
Journal of Ultrastructure Research, 1975The Fab′ fragment of McPC603 mouse myeloma immunoglobulin with phosphorylcholine-binding activity crystallizes into both a hexagonal and a cubic structure. Models of these structures showing approximate molecular packing were deduced from an electron microscopic examination of stained crystal sections, a preliminary X-ray diffraction study, and the ...
David M. Segal +3 more
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