Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus. [PDF]
, 1990 We quantitated and characterized the changes in the human B cell repertoire, at the clonal level, before and after immunization with rabies virus. Moreover, we generated 10 monoclonal cell lines producing IgM, IgG, and IgA antibodies to the virus.
Casali, P +6 more
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Advanced NanoBiomed Research, EarlyView.Perfluorocarbon‐based artificial oxygen carriers have long been of scientific interest for because they can be used as oxygen donors in medical applications. Lecithin‐modified nanoscale oxygen carriers (LENOX) are a newly designed nanoscaled emulsion based on perfluorodecalin, which is characterized by its compatibility with numerous clinically ...
Fabian Nocke +5 more
wiley +1 more source
Structural features of human immunoglobulin G that determine isotype-specific differences in complement activation. [PDF]
, 1993 Although very similar in sequence, the four subclasses of human immunoglobulin G (IgG) differ markedly in their ability to activate complement. Glu318-Lys320-Lys322 has been identified as a key binding motif for the first component of complement, C1q ...
Morrison, SL, Smith, RI, Tao, MH
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Staphylococci-induced Human Platelet Injury Mediated by Protein A and Immunoglobulin G Fc Fragment Receptor [PDF]
, 1979 Jack Hawiger +6 more
openalex +1 more source
Indeno[2,1‐c]fluorene Quasi[8]circulenes Through Intramolecular Cyclization
Angewandte Chemie International Edition, EarlyView.A new class of curved, chiral polycyclic aromatic hydrocarbon emerges from the fusion of indeno[2,1‐c]fluorene and quasi[8]circulene motifs. These redox‐active, antiaromatic scaffolds offer great synthetic utility, tunable properties, and modular functionalities for organic electronics and functional materials. Abstract The study of polycyclic aromatic
Eric Sidler +3 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap +12 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
The interaction of protein A and Fc fragment of rabbit immunoglobulin G as probed by complement-fixation and nuclear-magnetic-resonance studies [PDF]
, 1977 Craig Wright +4 more
openalex +1 more source
Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Interactions among rheumatoid synovial cells and monocyte-macrophages: production of collagenase-stimulating factor by human monocytes exposed to concanavalin A or immunoglobulin Fc fragments. [PDF]
, 1980 J.-M. Dayer +3 more
openalex +1 more source