Functional Molecule‐Integrated Nano‐Interfaces for Detection of Extracellular Vesicles
Functional molecule‐integrated nano‐interfaces for detection of extracellular vesicles prepared via template polymerization using multifunctional polymer–silica nanoparticle complex as a template followed by post‐functionalization modification are demonstrated.
Hirobumi Sunayama+2 more
wiley +1 more source
Understanding IgM Structure and Biology to Engineer New Antibody Therapeutics. [PDF]
Buchner J, Sitia R, Svilenov HL.
europepmc +1 more source
Hydrophobin‐Coated Echogenic Microbubbles for Molecular Targeting of Tumor Cells
Echogenic microbubbles based on hydrophobin and corresponding fusion protein (HFBI‐domZ) are developed as contrast agents for cancer diagnostics. Hydrophobin provides high stabilization of encapsulated perfluoro‐n‐butane, and fusion proteins allow further versatile functionalization with antibodies. In‐vitro experiments indicate that these microbubbles
Hedar H. Al‐Terke+8 more
wiley +1 more source
Integrating Biochemical and Computational Approaches Reveal Structural Insights in Trastuzumab scFv-Fc Antibody Engineering. [PDF]
Bednova O+9 more
europepmc +1 more source
Determination of the Primary Structure of a Mouse IgG2a Immunoglobulin: Amino‐Acid Sequence of the Fc Fragment [PDF]
Alain Bourgois+2 more
openalex +1 more source
This study reveals histone lactylation as a metabolic‐epigenetic regulator countering cellular senescence and skeletal muscle aging. Reduced lactylation impairs cell cycle, DNA repair and proteostasis pathways, while exercise restores glycolytic activity and lactylation levels, preserving muscle function.
Fanju Meng+16 more
wiley +1 more source
Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]
Zhou T+6 more
europepmc +1 more source
A thermochemical study of the reaction between protein A from S. aureus and fragment Fc from immunoglobulin G [PDF]
John Sjöquist, Ingemar Wadsö
openalex +1 more source
The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao+13 more
wiley +1 more source