Results 141 to 150 of about 45,350 (212)

Optimizing colloidal stability and viscosity of multispecific antibodies at the drug discovery-development interface: a systematic predictive case study. [PDF]

MAbs
Siegmund V, Klewinghaus D, Teroerde J, Pekar L, Harwardt J, Zielonka S, Militano F, Licari G, Evers A.   +8 more
europepmc   +1 more source

Harnessing Fc-Directed Bioconjugation for the Synthesis of Site-Specifically Modified Radioimmunoconjugates. [PDF]

Bioconjug Chem
Grimaldi C, Sebastiano J, Kao WM, Strugala E, McGlone SA, Watanabe T, Aoki T, Fujii T, Zeglis BM.   +8 more
europepmc   +1 more source

Trispecific SEED antibodies engineered for neutrophil-mediated cell killing. [PDF]

MAbs
Natale V, Heves G, Stadlbauer K, Rüker F, Siegmund V, Pekar L, Zielonka S, Toleikis L, Becker S, Wozniak-Knopp G.   +9 more
europepmc   +1 more source

Understanding mechanistic relationships between IgG titers and Fc effector functions: a computational framework to assess polyfunctionality. [PDF]

Front Immunol
Shoffner-Beck SK, Theisen RM, Wong KE, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kent S, Chung AW, Arnold KB.   +8 more
europepmc   +1 more source

Application and future prospects of bispecific antibodies in the treatment of non-small cell lung cancer. [PDF]

Cancer Biol Med
Wen J, Cui W, Yin X, Chen Y, Liu A, Wang Q, Meng X.   +6 more
europepmc   +1 more source

Combined <i>FCGR2A</i> (131H/R) and <i>FCGR3A</i> (158F/V) genotypes and their gender-specific association with chronic and refractory immune thrombocytopenia in Palestinian children. [PDF]

Front Med (Lausanne)
Amer K, Amer J, Taha AA, Baker W, Abuhamed A, Salhab A.   +5 more
europepmc   +1 more source

Effectiveness and safety of asfotase alfa for people with hypophosphatasia: a plain language summary of three studies. [PDF]

J Comp Eff Res
Jasmi FA, Belaya Z.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Chemical characterisation of the Fab and Fc fragments from surface immunoglobulin

Nature, 1980
Immunoglobulin (Ig) molecules of the M and D classes are present on the membranes of B lymphocytes (sIg), where they serve as antigen receptors1–6. sIg is a biosynthetically stable membrane protein which requires either denaturing conditions or detergents to free it from other membrane constituents1,7–9.
R. Parkhouse, J. Lifter, Y. S. Choi
semanticscholar   +4 more sources

Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1.

Journal of Molecular Biology, 2007
Removal of the fucose residue from the oligosaccharides attached to Asn297 of human immunoglobulin G1 (IgG1) results in a significant enhancement of antibody-dependent cellular cytotoxicity (ADCC) via improved IgG1 binding to Fcgamma receptor IIIa. To provide structural insight into the mechanisms of affinity enhancement, we determined the crystal ...
S. Matsumiya, Y. Yamaguchi, J. Saito, M. Nagano, H. Sasakawa, S. Otaki, M. Satoh, K. Shitara, Koichi Kato   +8 more
semanticscholar   +4 more sources