Results 161 to 170 of about 45,350 (212)

Interference with tolerance induction of primed B cells by the Fc fragment of immunoglobulin

Cellular Immunology, 1984
The capacity to interfere with tolerance induction in primed B cells was examined. Previous work had shown that TNP-specific splenic B cells from mice primed and boosted with TNP-KLH are highly susceptible to in vitro tolerization upon a brief exposure to TNP on a carrier unrelated to KLH.
Walker, S M, Fraker, P J, Weigle, W O
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Preliminary crystallographic study of the Fc fragment of a monoclonal IgG2b murine immunoglobulin

Journal of Molecular Biology, 1983
The Fe fragment of a gamma 2b murine monoclonal anti-p-azophenylarsonate antibody (R19.9, IgG2b, kappa) has been crystallized. The crystals are tetragonal, space group P41 (or P43) with unit cell dimensions: a = b = 134.3 +/- 1.1 A, c = 144.0 +/- 0.7 A.
Comarmond, M, Tougard, P
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NMR assignments of the N-glycans of the Fc fragment of mouse immunoglobulin G2b glycoprotein

Biomolecular NMR Assignments, 2021
The Fc portion of immunoglobulin G (IgG) promotes defensive effector functions in the immune system by interacting with Fcγ receptors and complement component C1q. These interactions critically depend on N-glycosylation at Asn297 of each CH2 domain, where biantennary complex-type oligosaccharides contain microheterogeneities resulting primarily from ...
Yoshiki Yamaguchi, Ichio Shimada, Koichi Kato, Koichi Kato, Rina Yogo, Rina Yogo, Takeshi Takizawa, Saeko Yanaka, Saeko Yanaka, Yohei Miyanoiri   +9 more
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IgC Fc fragments induce B cell differentiation and immunoglobulin secretion

Immunology Letters, 1989
We now show that the Fc fragment is capable of inducing B cell differentiation and secretion of immunoglobulins (Igs) in human mononuclear cells from peripheral blood (PBMC). The absolute number of plasma cells observed in all individuals tested is similar.
E.D. Carosella, J. Armand
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Unsusceptibility of recombinant human Fc fragments of immunoglobulin E to thrombin

Human Antibodies, 1996
Human immunoglobulin E (IgE) contains a potential recognition sequence for thrombin protease cleavage at N-terminal end of C epsilon 3 domain responsible for binding to alpha chain of high affinity Fc receptor for IgE (Fc epsilon RI alpha), but it remains unknown for the enzyme susceptibility.
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Effective treatment of experimental autoimmune neuritis with Fc fragment of human immunoglobulin

Journal of Neuroimmunology, 2007
IV immunoglobulin (IVIg) and its Fc fragment proved effective in preventing further progression of experimental autoimmune neuritis (EAN) in the rat induced by whole bovine peripheral nerve myelin and shortening disease duration. This effectiveness was associated with significant differences in electrophysiological parameters including less ...
Min-Xia Wang, Min-Xia Wang, Judith M. Spies, Judith M. Spies, John D. Pollard, John D. Pollard, Hsin Hsin Lin   +6 more
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Ultrastructure of the Fc fragment of human immunonoglobulin G

Immunochemistry, 1971
Abstract Crystals of the plasmin Fc fragment of human immunoglobulin G have been examined in the electron microscope at various stages during dissociation and recrystallization. Two characteristic shapes are recognized in the micrographs. One is a double, concentric annulus in which the outer annulus is seen to consist of 12 masses disposed radially ...
L. Pinteric, R H Painter, G. E. Connell
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Genetic (Gm) Antigens associated with Subfragments from the Fc Fragment of Human Immunoglobulin G [PDF]

Nature, 1969
THE specific (γ) polypeptide chain of immunoglobulin G (IgG, ref. 1) molecules carries several genetic markers (Gm antigens)2,3 which can be detected by serological techniques. Each of the markers is associated with one of three subclasses of γ chain, called γ1, γ2 or γ3 chains4.
M. W. Turner, Hans Bennich, L. Mårtensson, J. B. Natvig   +3 more
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Human Immunoglobulin A: Production of an Fc Fragment by an Enteric Microbial Proteolytic Enzyme

The Journal of Immunology, 1973
Summary An Fc fragment has been prepared in good yield by proteolytic cleavage of human secretory and serum myeloma IgA with an enzyme recovered from the human gastrointestinal tract. The naturally occurring enzyme is of microbial origin and its activity is metal dependent.
S K, Mehta, A G, Plaut, N J, Calvanico, T B, Tomasi   +3 more
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An improved protocol for large scale production of high purity ‘Fc’ fragment of human immunoglobulin G (IgG-Fc)

Journal of Chromatography B, 2020
We describe a simplified approach for purification and characterization of human 'IgG-Fc' fragment used widely as immunochemical tool and for therapeutic purposes. The 'Fc' fragment was purified from human IgG in a 3-stage column chromatography. The purified 'Fc' fragment appeared as a dimer glycoprotein with an apparent molecular mass of 52,981 Dalton
Unmesh Angre, Sanjeev Lala, Siddharth B. Daftary, Babasaheb U. Tandale, Shamkant B. Badgujar, Jatin B. Tandale, Vinod P. Gaur   +6 more
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