Results 161 to 170 of about 22,044 (247)

Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy. [PDF]

PLoS One
Lee T, Lee D, Jung E, Son M, Koo K, Choi J.   +5 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

CAR‐NK, a Splendid Strategy for Cancer, Especially for Gynecologic Tumor

Immunity, Inflammation and Disease, Volume 13, Issue 6, June 2025.
ABSTRACT Background NK cells are a class of innate lymphocytes capable of nonspecifically killing tumor cells without MHC restriction or prior sensitization. Recent advancements in biotechnology, particularly the development of chimeric antigen receptors (CAR) and related technologies, have enabled targeted tumor cell elimination.
Yisen Cao, Liying Wang, Liang Wang
wiley   +1 more source

The Association Between Neonatal Respiratory Distress Syndrome and Plasma IgG N-Glycosylation: A Case-Control Study. [PDF]

J Inflamm Res
Wang Y, Shen Q, Yan R, Wang M, Xu M, Chen H, Li D.   +6 more
europepmc   +1 more source

Corrigendum to “Structural Comparison of Fucosylated and Nonfucosylated Fc Fragments of Human Immunoglobulin G1” [J. Mol. Biol. 386/3 (2007) 767–779]

, 2011
S. Matsumiya, Yoshiki Yamaguchi, Junichi Saito, Mayumi Nagano, Hiroaki Sasakawa, Shizuo Otaki, Mitsuo Satoh, Kenya Shitara, Koichi Kato   +8 more
openalex   +1 more source

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling

iMeta, Volume 4, Issue 3, June 2025.
Compared to healthy controls, children with food‐sensitized tolerance and food allergy showed reduced fecal short‐chain fatty acids (SCFAs), particularly butyrate. In an ovalbumin‐sensitized mouse model, butyrate outperformed other SCFAs in alleviating allergic responses.
Jialu Shi, Wenjun Mao, Yuqing Song, Yuxin Wang, Lili Zhang, Yan Xu, Huiwen Gu, Siyu Yao, Yuanhang Yao, Zhifeng Liu, Vijaya Raghavan, Jin Wang   +11 more
wiley   +1 more source

Intranasal administration of a panreactive influenza antibody reveals Fc-independent mode of protection. [PDF]

Sci Rep
Beukenhorst AL, Rice KL, Frallicciardi J, Koldijk MH, Boudreau CM, Crawford J, Cornelissen LAHM, da Costa KAS, de Jong BA, Fischinger S, Julg B, Klap JM, Koch CM, Magyarics Z, Mohamed FAN, Okonkwo V, Adams L, McCarthy CM, Ronsard L, Temperton N, Vietsch H, Wichapong K, Ziere B, Lingwood D, Goudsmit J.   +24 more
europepmc   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

iMeta, Volume 4, Issue 3, June 2025.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang, Rong Li, Yasong Liu, Jinliang Liang, Yihang Gong, Cuicui Xiao, Jianye Cai, Tingting Wang, Qiang You, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Yingcai Zhang, Yang Yang, Hua Li, Jia Yao, Qi Zhang, Jun Zheng   +17 more
wiley   +1 more source

A Comprehensive Review of Fc Gamma Receptors and Their Role in Systemic Lupus Erythematosus. [PDF]

Int J Mol Sci
Sepúlveda-Delgado J, Llorente L, Hernández-Doño S.   +2 more
europepmc   +1 more source

Glutamatergic Regulation of miRNA‐Containing Intraluminal Vesicle Trafficking and Extracellular Vesicle Secretion From Cortical Neurons

Journal of Extracellular Vesicles, Volume 14, Issue 6, June 2025.
ABSTRACT Neuronal extracellular vesicles (microvesicles and exosomes) are emerging secreted vesicular signals that play important roles in the CNS. Currently, little is known about how glutamatergic signalling affects the subcellular localisation of exosome precursor intraluminal vesicles (ILVs), microRNA (miR) packaging into ILVs and in vivo spreading
Marcela Bertolio, Qiyi Li, Francesca E. Mowry, Kathryn E. Reynolds, Rashed Alananzeh, Haichao Wei, Kyoeun Keum, Rachel Jarvis, Jiaqian Wu, Yongjie Yang   +9 more
wiley   +1 more source