Results 161 to 170 of about 45,837 (320)

First successful protocol for desensitization to eptinezumab

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Eptinezumab is an anti‐calcitonin gene‐related peptide monoclonal antibody used for migraine prevention. During clinical trials, hypersensitivity to eptinezumab was described without a clear underlying mechanism. To determine if the reaction was immunoglobulin E–mediated, the team of Nice University Hospital (Nice, France) performed
Benoit Gerard   +8 more
wiley   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima   +9 more
wiley   +1 more source

Editing a gibberellin receptor gene improves yield and nitrogen fixation in soybean

open access: yesJournal of Integrative Plant Biology, EarlyView.
Knockout of the soybean gibberellin receptor gene GmGID1‐2 reduced plant height; strengthened stems; increased the number of branches, nodes, pods, and seeds; and improved yield, seed oil content and nitrogen fixation. ABSTRACT Soybean is an important source of oil, protein, and feed. However, its yield is far below that of major cereal crops.
Jiajun Tang   +11 more
wiley   +1 more source

IdeZ protease does not prevent convertase stabilization by C3 nephritic factors in C3 glomerulopathy. [PDF]

open access: yesNephrol Dial Transplant
Stevens KH   +4 more
europepmc   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini   +9 more
wiley   +1 more source

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