Results 161 to 170 of about 51,720 (301)

Impaired Immunoglobulin G Fc Fragment Function in Diabetics is Caused by a Mechanism Different from Glycation [PDF]

, 1994
Roswitha Dolhofer-Bliesener, Brigitte Lechner, Klaus-Dieter Gerbitz   +2 more
openalex   +1 more source

Evaluation of a Virus-like Nanoparticle Porcine Circovirus Type-2 (PCV2) Capsid Protein Fused with the Pig Immunoglobulin Fc Fragment as a Novel Vaccine Candidate against PCV2 in Mice [PDF]

, 2021
Qingping Luo, Waqas Ahmed, Yichen Dai, Ali Mohsin, Haifeng Hang, Yingping Zhuang, Meijin Guo   +6 more
openalex   +1 more source

Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol‐related liver fibrosis

British Journal of Pharmacology, EarlyView.
Background and Purpose Chronic liver disease and hepatic fibrosis constitute a threat to global health. Clinical translation of preclinical research has been limited, highlighting an urgent need for novel treatments. Cyclophilin inhibitors have shown beneficial effects in liver disease; however, the underlying mechanism of action and the effect across ...
Una Rastovic, Sara Campinoti, Lai Wei, Bruna Almeida, Sergio Francesco Bozzano, Ramin Amiri, Nicola Harris, Omolola Ajayi, Tsin Shue Koay, Caoimhe Kerins, Fiona N. Kenny, Ane Zamalloa, Lissette Adofina, Rosa Miquel, Yoh Zen, Parthi Srinivasan, Krishna Menon, Nigel Heaton, Camilla Luni, Eileen Gentleman, Tanya Shaw, Daren Ure, Shilpa Chokshi, Luca Urbani, Elena Palma   +24 more
wiley   +1 more source

IdeZ protease does not prevent convertase stabilization by C3 nephritic factors in C3 glomerulopathy. [PDF]

Nephrol Dial Transplant
Stevens KH, Baas LM, van de Kar NCAJ, van den Heuvel LPWJ, Michels MAHM.   +4 more
europepmc   +1 more source

CTCF Is Essential for the Development and Maintenance of CALM‐AF10‐Induced Leukemia

Cancer Science, EarlyView.
CTCF regulates TGM2 gene expression by modulating key histone modifications, including increased acetylation of H3K27 (H3K27ac) and trimethylation of H3K4 (H3K4me3), along with decreased trimethylation of H3K27 (H3K27me3). These epigenetic changes are critical for maintaining the stem‐like properties of CALM‐AF10‐induced AML. Pharmacological inhibition
Yoko Kuroki, Kazutsune Yamagata, Yukiko Aikawa, Yutaka Shima, Hisafumi Shioneri, Issay Kitabayashi   +5 more
wiley   +1 more source

Exploring glycoform-dependent dynamic modulations in human immunoglobulin G via computational and experimental approaches. [PDF]

Proc Natl Acad Sci U S A
Yanaka S, Sakae Y, Miyanoiri Y, Yamaguchi T, Isono Y, Kondo S, Iwasaki M, Onitsuka M, Yagi H, Kato K.   +9 more
europepmc   +1 more source

Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties [PDF]

, 2010
Gordana Wozniak‐Knopp, Stefan Bartl, Anna Bauer, M. Mostageer, Maximilian Woisetschläger, B Antes, K. Ettl, Marion Kainer, G. Weberhofer, Susanne Wiederkum, Gottfried Himmler, Geert C. Mudde, Florian Rüker   +12 more
openalex   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Fc-Afucosylation of VAR2CSA-Specific Immunoglobulin G and Clinical Immunity to Placental Plasmodium falciparum Malaria. [PDF]

J Infect Dis
Lopez-Perez M, Viwami F, Ampomah P, Šuštić T, Larsen MD, Wuhrer M, Vidarsson G, Ofori MF, Tuikue Ndam N, Hviid L.   +9 more
europepmc   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core