Results 161 to 170 of about 90,091 (319)

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

A note on FC-nilpotency [PDF]

open access: yesarXiv, 2016
The notion of bounded FC-nilpotent group is introduced and it is shown that any such group is nilpotent-by-finite, generalizing a result of Neumann on bounded FC-groups.
arxiv  

Helicobacter pylori CagA elevates FTO to induce gastric cancer progression via a “hit‐and‐run” paradigm

open access: yesCancer Communications, EarlyView.
Abstract Background Helicobacter pylori (H. pylori) infection contributes significantly to gastric cancer (GC) progression. The intrinsic mechanisms of H. pylori‐host interactions and their role in promoting GC progression need further investigation.
Bing He   +10 more
wiley   +1 more source

Obstacles to the Collisional Growth of Planetesimals [PDF]

open access: yesarXiv, 2003
The debate over whether kilometer-sized solids, or planetesimals, assemble by collision-induced chemical sticking or by gravity-driven unstable modes remains unsettled. In light of recent work showing that gravitational growth can occur despite turbulent stirring, we critically evaluate the collisional hypothesis.
arxiv  

Staphylococci-induced Human Platelet Injury Mediated by Protein A and Immunoglobulin G Fc Fragment Receptor [PDF]

open access: bronze, 1979
Jack Hawiger   +6 more
openalex   +1 more source

Blocking ITGA5 potentiates the efficacy of anti‐PD‐1 therapy on glioblastoma by remodeling tumor‐associated macrophages

open access: yesCancer Communications, EarlyView.
Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao   +11 more
wiley   +1 more source

On Fourier Coefficients of GL(n)-Automorphic Functions over Number Fields [PDF]

open access: yesarXiv, 2017
We study Fourier coefficients of $GL_n(\A)$-automorphic functions $\phi$, for $\A$ being the adele group of a number field $\kkk$. Let FC be an abbreviation for such a Fourier coefficient (and FCs for plural). Roughly speaking, in the present paper we process FCs by iteratively using the operations: Fourier expansions, certain exchanges of Fourier ...
arxiv  

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

open access: yesCancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang   +11 more
wiley   +1 more source

Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice. [PDF]

open access: yes, 1993
We have generated transgenic mice that express the immunoglobulin (Ig)M heavy chain and kappa light chain genes coding for a human IgM rheumatoid factor (RF), Les.
Carson, DA   +6 more
core  

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