Results 191 to 200 of about 90,091 (319)

Backbone 1H, 13C, and 15N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein [PDF]

open access: hybrid, 2014
Hirokazu Yagi   +6 more
openalex   +1 more source

Loss of Tapasin in Tumors Potentiates T‐Cell Recognition and Anti‐Tumor Effects of Immune Checkpoint Blockade

open access: yesCancer Science, EarlyView.
Impaired tapasin expression enhances the recognition of tumor cells by CD8+ T cells and the anti‐tumor effects of immune checkpoint blockade. ABSTRACT Tumors can evade host immune surveillance by compromising the intracellular antigen processing machinery (APM), such as beta 2 macroglobulin (β2m) or the transporter associated with antigen processing ...
Keigo Moniwa   +9 more
wiley   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

open access: yesCell Proliferation, EarlyView.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou   +18 more
wiley   +1 more source

Osteohistological signal from the smallest known phytosaur femur reveals slow growth and new insights into the evolution of growth in Archosauria

open access: yesJournal of Anatomy, EarlyView.
The paucity of small, skeletally immature individuals representing the earliest ontogenetic stages of extinct archosaurs complicates our understanding of the growth dynamics within and between species. The opportune finding of the smallest phytosaur femora reveals slow growth, a surprising signal considering that larger phytosaurs in North America have
Erika R. Goldsmith   +6 more
wiley   +1 more source

Integrative Genomics Refines Tissues, Candidate Genes and Putative Regulatory Links Involved in the Humic Adaptation of Keystone Freshwater Fish

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Although population genomics approaches have been successful in identifying regions of the genome shaped by natural selection, progress in dissecting the molecular mechanisms of adaptive variants and traits has been slow. By integrating multi‐tissue (gill, spleen, olfactory rosette, whole eye, and liver) transcriptomes from 16 wild Eurasian ...
M. Yu. Ozerov   +4 more
wiley   +1 more source

Pleomorphic adenoma and carcinoma ex‐pleomorphic adenoma tumorigenesis: A proteomic analysis

open access: yesOral Diseases, EarlyView.
Abstract Objectives To conduct a comprehensive proteomic analysis of normal salivary gland tissue, pleomorphic adenoma (PA), and carcinoma ex‐pleomorphic adenoma (CXPA), and validate the proteomic findings using immunohistochemistry. Methods Six normal salivary gland tissues, seven PA and seven CXPA samples underwent laser microdissection followed by ...
Virgílio Gonzales Zanella   +13 more
wiley   +1 more source

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