Results 191 to 200 of about 45,837 (320)

Does a Polycistronic 2A Design Enable Functional FcRn Production for Antibody Pharmacokinetic Studies? [PDF]

Pharmaceutics
Nesmeyanova VS, Ushkalenko ND, Olkin SE, Kosenko MN, Rukhlova EA, Susloparov IM, Shcherbakov DN.   +6 more
europepmc   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

HCB101: a novel potent ligand-trap Fc-fusion protein targeting the CD47-SIRPα pathway with high safety and preclinical efficacy for hematological and solid tumors. [PDF]

J Hematol Oncol
Wang JT, Tseng CL, Teng HF, Kuo PH, Cheng YC, Chen YJ, Lu YH, Wang CC, Shen TK, Wang HF, Tsai PL, Wu YC, Ho CH, Sun WT, Li YC, Lee YH, Hung YJ, Chen M, Li Z, Juo ZS, Zhai W, Liu SS.   +21 more
europepmc   +1 more source

X-Ray Crystallographic Studies of the Fab and Fc Fragments of Human Myeloma Immunoglobulins

Cold Spring Harbor Symposia on Quantitative Biology, 1972
R J, Poljak, L M, Amzel, H P, Avey, L N, Becka, D J, Goldstein, R L, Humphrey   +5 more
openaire   +2 more sources

ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse

Experimental Physiology, EarlyView.
Abstract The objective of this work was to investigate the role of ZFP36 in mitral valve prolapse (MVP). Mitral valve and plasma were collected to assess the expression of ZFP36, transforming growth factor β (TGF‐β), collagen and elastin and apoptosis rates.
Meng Zhao, Zhaoyi Zhu, Yawei Dai, Li Jiang, Qihan Wen, Yingjie Zhang, Qingyang Shi, Yihu Tang, Jingxin Zhou, Yanhu Wu   +9 more
wiley   +1 more source

Fc-Afucosylation of VAR2CSA-Specific Immunoglobulin G and Clinical Immunity to Placental Plasmodium falciparum Malaria. [PDF]

J Infect Dis
Lopez-Perez M, Viwami F, Ampomah P, Šuštić T, Larsen MD, Wuhrer M, Vidarsson G, Ofori MF, Tuikue Ndam N, Hviid L.   +9 more
europepmc   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

International Journal of Cancer, Volume 158, Issue 4, Page 994-1007, 15 February 2026.
What's new? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu, Annika Lauk, David Sedloev, Josephine Brysting, Ela Cetin, Chunan Liu, Maximilian Mönnig, Thomas Luft, Haiyang Yun, Michael Schmitt, Tim Sauer, Fengbiao Zhou, Christian Rohde, Carsten Müller‐Tidow   +13 more
wiley   +1 more source

Methods for Conjugating Antibodies with Quantum Dots. [PDF]

Molecules
Sokolov P, Knysh A, Kriukova I, Samokhvalov P, Kistenev YV.   +4 more
europepmc   +1 more source

Multifunctional Carbon Fiber–Nanotube Frameworks for Safe, Recyclable, High‐Performance Lithium‐Ion Batteries

Battery Energy, Volume 5, Issue 1, January 2026.
Schematic illustration for the synthesis of CFCNT based modified current collector and structure of pouch cell demonstrating arrangements of electrodes and separator. ABSTRACT This study introduces a multifunctional carbon fiber–carbon nanotube (CFCNT) architecture as a lightweight, thermally stable, and recyclable current collector for lithium‐ion ...
Ritu Malik, Vijay K. Tomer, Denise Byrne, Mohini Sain   +3 more
wiley   +1 more source

Engineering a novel light-chain single-domain antibody to enable IgG-format bispecific antibody design. [PDF]

Antib Ther
Wang M, Xu Q, Kong Y, Zhong Y, Yin F, Liu L, Yang Z, Ying T, Wu Y.   +8 more
europepmc   +1 more source