Results 231 to 240 of about 45,837 (320)

CD Molecules Nomenclature 2025: Antibody Validation and Expression Profiling of Immune System G Protein‐Coupled Receptors

open access: yesEuropean Journal of Immunology, Volume 55, Issue 12, December 2025.
HLDA Workshops were established 40 years ago to develop a standardized CD molecule nomenclature for leukocyte cell‐surface molecules by comparing monoclonal antibodies (mAbs) produced by different laboratories and companies. The HLDA11 Workshop focused on validating G‐protein‐coupled receptors (GPCRs) targeting mAbs and assessing cell‐type‐specific ...
Javier Fernández‐Calles   +9 more
wiley   +1 more source

Half-Life Extension of the IgG-Degrading Enzyme (IdeS) Using Fc-Fusion Technology. [PDF]

open access: yesEur J Immunol
Daventure V   +7 more
europepmc   +1 more source

Functional differences between CLL‐ and ALL‐derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL‐10 as potential modulatory targets

open access: yesHemaSphere, Volume 9, Issue 12, December 2025.
Abstract Despite advances in targeted therapies, treatment of chronic lymphocytic leukemia (CLL) remains challenging, highlighting the urgent need for effective new therapeutic strategies. Although chimeric antigen receptor (CAR) T‐cell therapy dramatically improved outcomes in acute lymphoblastic leukemia (ALL), its efficacy in CLL is limited.
Janin Dingfelder   +15 more
wiley   +1 more source

Pathways Contributing to Chemotherapy‐Induced Myotoxicity Are Attenuated by EPA + DHA in a Clinically Relevant Model of Colorectal Cancer

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Skeletal muscle loss is a well‐recognized consequence of cancer, and chemotherapy exacerbates myotoxicity through multiple mechanisms. Retaining muscle mass improves tumour response to therapies and tolerance to chemotherapy; hence, interventions to mitigate myotoxicity warrant investigations.
Peter O. Isesele   +4 more
wiley   +1 more source

Desensitization With Imlifidase: Overcoming Immunological Barriers in Kidney Transplantation. [PDF]

open access: yesKidney Med
Hernández-Velasco PJ   +6 more
europepmc   +1 more source

Targeted Therapy for Idiopathic Inflammatory Myopathy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune disorders characterized by chronic muscle inflammation and significant extramuscular involvement. A substantial proportion of patients exhibit refractory or relapsing disease despite conventional immunosuppressive therapies, necessitating the ...
Ruijie Wang   +3 more
wiley   +1 more source

Engineered Low‐Endotoxin Bacterial Biomimetic Vesicles for Enhanced Oral Dual‐Antigen Subunit Vaccine Delivery

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
A genetically engineered low‐endotoxin Salmonella choleraesuis biomimetic vesicle (CSS‐BBV), coated with COS, is utilized to enhance the oral delivery efficacy of subunit vaccines. The modular SpyCatcher/SpG design enables rapid dual‐antigen conjugation, providing a versatile platform for the development of infectious disease vaccines. ABSTRACT Subunit
Xuegang Shen   +11 more
wiley   +1 more source

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