Results 271 to 280 of about 76,339 (318)

Preliminary crystallographic study of the Fc fragment of a monoclonal IgG2b murine immunoglobulin

Journal of Molecular Biology, 1983
The Fe fragment of a gamma 2b murine monoclonal anti-p-azophenylarsonate antibody (R19.9, IgG2b, kappa) has been crystallized. The crystals are tetragonal, space group P41 (or P43) with unit cell dimensions: a = b = 134.3 +/- 1.1 A, c = 144.0 +/- 0.7 A.
Comarmond, M, Tougard, P
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Studies on human immunoglobulin G Fc sub-fragments. Structural requirements for biological expression

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1970
Abstract Sub-fragments of the Fc segment of normal human immunoglobulin G have been obtained by papain and pepsin hydrolysis. A comparative study of their physicochemical characteristics and biological activities has been conducted. Except for the Gm “1” allotypic marker, the pepsin sub-fragment, with a molecular weight of half that of Fc, retained ...
D, Frommel, R, Hong
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Genetic (Gm) Antigens associated with Subfragments from the Fc Fragment of Human Immunoglobulin G

Nature, 1969
THE specific (γ) polypeptide chain of immunoglobulin G (IgG, ref. 1) molecules carries several genetic markers (Gm antigens)2,3 which can be detected by serological techniques. Each of the markers is associated with one of three subclasses of γ chain, called γ1, γ2 or γ3 chains4.
M W, Turner, L, Mårtensson, J B, Natvig, H, Bennich   +3 more
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Interference with tolerance induction of primed B cells by the Fc fragment of immunoglobulin

Cellular Immunology, 1984
The capacity to interfere with tolerance induction in primed B cells was examined. Previous work had shown that TNP-specific splenic B cells from mice primed and boosted with TNP-KLH are highly susceptible to in vitro tolerization upon a brief exposure to TNP on a carrier unrelated to KLH.
Walker, S M, Fraker, P J, Weigle, W O
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Aggregated immunoglobulin and Fc fragment of IgG induce IL-6 release from human monocytes

Cellular Immunology, 1990
The Fc fragment of immunoglobulin (Ig) has been shown to play an important role in the regulation of humoral immunity, cellular immunity, lymphocyte and monocyte activation, and immune mediator secretion. We wished to determine if Ig or Fc fragments would induce IL-6 production from monocytes.
Z D, Ling, H J, Ziltener, B T, Webb, D S, Matheson   +3 more
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Human Immunoglobulin A: Production of an Fc Fragment by an Enteric Microbial Proteolytic Enzyme

The Journal of Immunology, 1973
Summary An Fc fragment has been prepared in good yield by proteolytic cleavage of human secretory and serum myeloma IgA with an enzyme recovered from the human gastrointestinal tract. The naturally occurring enzyme is of microbial origin and its activity is metal dependent.
S K, Mehta, A G, Plaut, N J, Calvanico, T B, Tomasi   +3 more
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[Isolation of FAB and Fc fragments from murine immunoglobulin G1].

Biulleten' eksperimental'noi biologii i meditsiny, 1979
Two methods of isolating Fab- and Fc-fragments from mouse immunoglobulin G1 are presented. The first method involves fractionation of papain protein hydrolysate on a column with DEAE- (or DE-32)-cellulose adjusted with 0.005 M K-phosphate buffer, pH 8. The Fab-fragment was eluted from the column with the starting buffer.
E L, Beliaeva, B V, Nikonenko, E V, Sidorova   +2 more
openaire   +1 more source

An easy and simple separation method for Fc and Fab fragments from chicken immunoglobulin Y (IgY).

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020
Xin Zhou, Yanru Wang, D. Ahn, Z. Cai
semanticscholar   +1 more source

Expression of Fc fragment receptors of immunoglobulin G (Fc gammaRs) in rat hepatic stellate cells.

Digestive diseases and sciences, 2005
Hepatic stellate cells (HSCs) are now considered the major cell type in the liver mediating the development of liver fibrosis. Recently it was demonstrated that HSCs express membrane proteins involved in antigen presentation. We further evaluate immunological properties of HSCs by examining the expression and function of the Fc fragment of ...
Hong, Shen, Manna, Zhang, Kelly, Kaita, Gerald Y, Minuk, Julia, Rempel, Yuewen, Gong   +5 more
openaire   +1 more source

Fc fragments of immunoglobulin G are an inductor of regulatory rheumatoid factor and a promising therapeutic agent for rheumatic diseases.

International Journal of Biological Macromolecules, 2017
A. Sidorov, L. Beduleva, I. Menshikov, A. Terentiev, E. Stolyarova, Nadezhda Abisheva   +5 more
semanticscholar   +1 more source