Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Autoimmune heparin-induced thrombocytopenia following cardiac surgery. [PDF]
St Bernard R, Nazy I, Warkentin TE.
europepmc +1 more source
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang +10 more
wiley +1 more source
Post-Transfusion Purpura: A Clinical Case With Alveolar Haemorrhage. [PDF]
Yamakova Y +3 more
europepmc +1 more source
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li +17 more
wiley +1 more source
Production and Characterization of Recombinant Single-Chain Variable Fragment (scFv) Antibody Against <i>Fasciola gigantica</i> Saposin-like Protein 2. [PDF]
Rattanasroi K +5 more
europepmc +1 more source
From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil +3 more
wiley +1 more source
Immunoglobulin G complexes from post-infectious ME/CFS, including post-COVID ME/CFS disrupt cellular energetics and alter inflammatory marker secretion. [PDF]
Liu Z +16 more
europepmc +1 more source
Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley +1 more source
Immune complex handling in transplantation: central roles for complement factor H, animal models, and translational implications. [PDF]
Quigg RJ, Alexander JJ.
europepmc +1 more source

