Results 191 to 200 of about 158,982 (309)

Functional characterization of the polar organizer protein FimV in <i>Pseudomonas putida</i>. [PDF]

J Bacteriol
Schmidt LM, Pulido-Sánchez M, Treuner-Lange A, Zehner L, López-Sánchez A, Cava F, Govantes F, Thormann KM.   +7 more
europepmc   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Hybrid Supercharged Antibodies: A Rational Approach to Boost Immunoassay Sensitivity via Controlled Nanoparticle Adsorption. [PDF]

Langmuir
Sato J, Kasahara K, Nagatoishi S, Murakami K, Kuroda D, Caaveiro JMM, Nagai H, Tsumoto K.   +7 more
europepmc   +1 more source

Proteolysis of defensive proteins in peritonitis exudate [PDF]

, 1991
Assfalg-Machleidt, Irmgard, Billing, A., Fröhlich, D., Jochum, Marianne, Machleidt, W.   +4 more
core   +1 more source

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs, Pranay Nath, Alice Chen, Rizwan Romee, Andreia Maia   +4 more
wiley   +1 more source

Unlabeled NMR Approach with Site-Specific Methyl Assignments for Structural Evaluation of the IgG1 Fc Region. [PDF]

J Am Chem Soc
Yanaka S, Koseki Y, Miyanoiri Y, Yamazaki T, Terauchi T, Kaneko D, Isono Y, Tomita K, Kondo S, Onitsuka M, Yagi-Utsumi M, Yagi H, Ishii-Watabe A, Kato K.   +13 more
europepmc   +1 more source

Autoimmunity to Pancreatic juice in Crohn´s Disease [PDF]

, 1987
Finkbeiner, H., Lehnert, Peter, Normann, D., Otte, M., Stöcker, K., Stöcker, W., Ulrich, S.   +6 more
core  

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

Effect of Mutations in the C-Terminal 22-24 Domains of Filamin C Associated with Cardio- and Myopathies on Its Interaction with Small Heat Shock Protein HspB7. [PDF]

Int J Mol Sci
Muranova LK, Vostrikova VM, Gusev NB.
europepmc   +1 more source

Fragmentation and reduction of porcine 19 S immunoglobulin M [PDF]

FEBS Letters, 1974
openaire   +2 more sources