Results 41 to 50 of about 167,466 (331)
Proceedings of the National Academy of Sciences of the United States of America, 1982 The consistent appearance of specific chromosomal translocations in human Burkitt lymphomas and murine plasmacytomas has suggested that these translocations might play a role in malignant transformation. Here we show that transformation of these cells is
R. Taub +7 more
semanticscholar +1 more source
Immunoglobulin heavy chain patterns in reactive lymphadenopathy. [PDF]
Journal of Clinical Pathology, 1991 Thirty one lymph nodes taken from 24 benign reactive cases, three cases of angiolymphoid hyperplasia with eosinophilia, one case of Kimura's disease and three cases of Hodgkin's disease, were stained for immunoglobulin heavy chains IgG, IgM, IgA and IgE using the peroxidase-antiperoxidase method.
T Rhodes, M Sundaresan, A B Akosa
openaire +3 more sources
Genes & Development, 2014 MZB1 (pERp1) is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. Rosenbaum et al.
M. Rosenbaum +6 more
semanticscholar +1 more source
The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains. [PDF]
PLoS ONE, 2015 The leukocyte immunoglobulin-like receptor (LILR) family includes inhibitory and stimulatory members which bind to classical and non-classical HLA-class I.
Zhiyong Zhang +6 more
doaj +1 more source
The Translation in vitro of mRNA for Immunoglobulin Heavy Chains [PDF]
European Journal of Biochemistry, 1973 The addition of mRNA preparations to a number of heterologous cell‐free systems has been shown to result in the synthesis of immunoglobulin light chains. This paper reports the results of experiments in which an mRNA fraction prepared from MOPC 21 mouse myeloma cells has been used to stimulate the synthesis of immunoglobulin heavy chains in rabbit ...
N.J. Cowan, Cesar Milstein
openaire +3 more sources
A preliminary analysis of the immunoglobulin genes in the African elephant (Loxodonta africana). [PDF]
PLoS ONE, 2011 The genomic organization of the IgH (Immunoglobulin heavy chain), Igκ (Immunoglobulin kappa chain), and Igλ (Immunoglobulin lambda chain) loci in the African elephant (Loxodonta africana) was annotated using available genome data.
Yongchen Guo +6 more
doaj +1 more source
BioMedInformatics, 2023 Human immunoglobulin allotypes are allelic antigenic determinants (or “markers”) determined serologically, classically by hemagglutination inhibition, on the human immunoglobulin (IG) or antibody heavy and light chains. The allotypes have been identified
Marie-Paule Lefranc, Gérard Lefranc
doaj +1 more source
Haematologica, 2014 Primary established genetic abnormalities in B-cell precursor acute lymphoblastic leukemia include high hyperdiploidy (51–65 chromosomes), the translocations t(12;21)(p13;q22)/ETV6-RUNX1 fusion and t(9;22)(q34;q11)/BCR-ABL1 fusion, MLL rearrangements and
Sally J. Jeffries +3 more
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Exceptionally long CDR3H are not isotype restricted in bovine immunoglobulins. [PDF]
PLoS ONE, 2013 Exceptionally long third complementarity determining regions of the heavy chain (CDR3H) were previously described as a specificity of bovine IgG and IgM immunoglobulins.
Stefanie Walther +2 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source