The Immunoglobulins of Cold-Blooded Vertebrates [PDF]
, 2014 Peer reviewedPublisher ...
Chen +22 more
core +2 more sources
Frontiers in Cell and Developmental Biology, 2020 Somatic hypermutation (SHM) status provides an important prognostic indicator for chronic lymphocytic leukemia (CLL), a very common type of mature B-cell leukemia.
Sanjeev Kumar Gupta +2 more
doaj +1 more source
Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein [PDF]
, 1995 Background: Heavy-chain diseases (HCDs) are human lymphoproliferative neoplasias that are characterized by the secretion of truncated immunoglobulin heavy chains devoid of light chains.
Bucchini, Danielle +6 more
core +1 more source
Immunoglobulin heavy chain patterns in reactive lymphadenopathy. [PDF]
Journal of Clinical Pathology, 1991 Thirty one lymph nodes taken from 24 benign reactive cases, three cases of angiolymphoid hyperplasia with eosinophilia, one case of Kimura's disease and three cases of Hodgkin's disease, were stained for immunoglobulin heavy chains IgG, IgM, IgA and IgE using the peroxidase-antiperoxidase method.
T Rhodes, M Sundaresan, A B Akosa
openaire +3 more sources
Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data [PDF]
PLoS Comput Biol 15(7): e1007133 (2019), 2017 The collection of immunoglobulin genes in an individual's germline, which gives rise to B cell receptors via recombination, is known to vary significantly across individuals. In humans, for example, each individual has only a fraction of the several hundred known V alleles.
arxiv +1 more source
Inference of B cell clonal families using heavy/light chain pairing information [PDF]
, 2022 Next generation sequencing of B cell receptor (BCR) repertoires has become a ubiquitous tool for understanding the antibody-mediated immune response: it is now common to have large volumes of sequence data coding for both the heavy and light chain subunits of the BCR.
arxiv +1 more source
Monoclonal immunoglobulin heavy chain gene rearrangement in Fuchs’ uveitis
BMC Ophthalmology, 2018 Background Fuchs’ uveitis (FU) is occasionarlly complicated with heavy vitreous opacity. We have performed vitrectomy procedures to remove vitreous opacity in affected patients as part of differential diagnosis for primary vitreoretinal lymphoma (PVRL ...
Hisae Nakahara +10 more
doaj +1 more source
Non-Gaussian polymers described by alpha-stable chain statistics: model, applications and effective interactions in binary mixtures [PDF]
Phys. Rev. E, 91, 5, 052602 (2015), 2015 The Gaussian chain model is the classical description of a polymeric chain, which provides the analytical results regarding end-to-end distance, the distribution of segments around the mass center of a chain, coarse grained interactions between two chains and effective interactions in binary mixtures.
arxiv +1 more source
The Translation in vitro of mRNA for Immunoglobulin Heavy Chains [PDF]
European Journal of Biochemistry, 1973 The addition of mRNA preparations to a number of heterologous cell‐free systems has been shown to result in the synthesis of immunoglobulin light chains. This paper reports the results of experiments in which an mRNA fraction prepared from MOPC 21 mouse myeloma cells has been used to stimulate the synthesis of immunoglobulin heavy chains in rabbit ...
N.J. Cowan, Cesar Milstein
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The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains. [PDF]
PLoS ONE, 2015 The leukocyte immunoglobulin-like receptor (LILR) family includes inhibitory and stimulatory members which bind to classical and non-classical HLA-class I.
Zhiyong Zhang +6 more
doaj +1 more source