Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47
Cancer Communications, EarlyView.Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang +20 more
wiley +1 more source
The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene [PDF]
, 1989 J. Christopher Grimaldi, TC Meeker
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Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains. [PDF]
Data Brief, 2018 Thörnqvist L, Ohlin M.
europepmc +1 more source
Sequence of Amino Acids of the NH2‐Terminal Region of a Mouse‐Clonal Immunoglobulin Heavy Chain [PDF]
, 1972 Alain Bourgois +2 more
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Isolation of mRNA coding for immunoglobulin heavy chain [PDF]
Proceedings of the National Academy of Sciences, 1975 A. R. Williamson, Ronald H. Stevens
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Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele
Chronic Diseases and Translational Medicine, EarlyView.Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin +5 more
wiley +1 more source
The nucleotide sequence of a human immnnoglobulin C-gamma-1 gene [PDF]
, 1982 We report the nucleotide sequence of a gene encoding the constant region of a human immnnoglobulin γ1 heavy chain (Cγ1). A comparison of this sequence with those of the Cγ2 and Cγ4 genes reveals that these three human Cγ genes share considerable homology
Berson, Bennett J. +2 more
core
Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal Relationships. [PDF]
J Immunol, 2019 Zhou JQ, Kleinstein SH.
europepmc +1 more source
ChemPlusChem, EarlyView.Bioglycerol, the primary byproduct of biodiesel production, has the potential to be valorized as a cosolvent in industrial formulations. Surface tension and self‐diffusion data reveal that rhamnolipid self‐aggregation in water is poorly affected by the addition of bioglycerol up to very high concentrations. These results demonstrate that biosurfactants
Rodolfo Esposito +8 more
wiley +1 more source
Cytometry Part A, EarlyView.ABSTRACT Antibody titration is an important step in every cytometric workflow, with the goal being to determine antibody concentrations that ensure highly reproducible results. When aiming to compare antigen expression between samples using mean or median fluorescence intensity (MFI), reagents should be used at a saturating concentration so that ...
Natalie Smith +2 more
wiley +1 more source