Development of a Bioinformatics Framework for the Detection of Gene Conversion and the Analysis of Combinatorial Diversity in Immunoglobulin Heavy Chains in Four Cattle Breeds. [PDF]
Walther S+4 more
europepmc +1 more source
Distribution and Association of Heavy and Light Chain Variable Region Subgroups among Human IgA Immunoglobulins [PDF]
J. Donald Capra, J. Michael Kehoe
openalex +1 more source
Pre‐oviposition development of the brown anole (Anolis sagrei)
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling+9 more
wiley +1 more source
A hereditary immunoglobulin A abnormality: absence of light-heavy—chain assembly [PDF]
Chaya Moroz, Jacob Amir, André de Vries
openalex +1 more source
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler+4 more
wiley +1 more source
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen+7 more
wiley +1 more source
Binding Studies on Heavy-Light Chain Recombinant Hybrid Immunoglobulins a Derived from Murine Myeloma Anti-Fructofuranans [PDF]
Dirk G. Streefkerk+2 more
openalex +1 more source
New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the ...
Alessandra Ghigo+22 more
wiley +1 more source
Structural Studies of a Heavy Chain from a Mouse Immunoglobulin M with Antibody Activity
Elizabeth A. Robinson+2 more
openalex +1 more source
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley +1 more source