Results 231 to 240 of about 1,441,564 (292)

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

The Journal of Dermatology, EarlyView.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du, Anika Jallorina, Toru Yoshino, Lingyu Bao, Han Bao, Victor Chang, Henry K. Wong, Derek V. Chan, Stephen K. Richardson, Mary F. Lee‐Wong   +9 more
wiley   +1 more source

Discordance between immunofixation and free light chain assays in multiple myeloma: a retrospective analysis and evaluation of the heavy/light chain assay for disease monitoring. [PDF]

Blood Res
Nathalang O, Onthong Y, Laoruangroj C, Apipongrat D.   +3 more
europepmc   +1 more source

Weekend Overload: Day‐to‐Day Fluctuations of Outdoor Recreation Affect Wild Mammals' Space‐Use in a Popular Forest Reserve Near Florence, Italy

Animal Conservation, EarlyView.
In an urban‐adjacent forested area, we investigated the spatial and temporal distribution of the wild mammal community in relation to day‐to‐day fluctuations of human presence occurring between working days and weekends. We deployed 52 camera‐traps systematically within an EU Natura 2000 area located within the metropolitan area of Florence, central ...
Ilaria Greco, Marco Salvatori, Claudio Bruzzone, Gianluca Serra, Giovanni Galipò, Davide Travaglini, Francesco Rovero   +6 more
wiley   +1 more source

Executive summary of the European consensus report on the diagnosis and treatment of monoclonal gammopathy of renal significance. [PDF]

Clin Kidney J
Sprangers B, Cohen C, Gnemmi V, Shabaka A, Fernandez-Juarez G, van Midden D, Steenbergen E, Milani P, Vignon M, Wilde B, Hegenbart U, Wetzels JF.   +11 more
europepmc   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Revised porcine IgG subclass classification based on innate immune cell activation. [PDF]

Front Immunol
Van der Weken H, Helsmoortel C, Van Iseghem J, Dierick M, Devriendt B.   +4 more
europepmc   +1 more source

Determinants of Immunoglobulin‐G N‐Glycan Patterns in the Aging General Population

Allergy, EarlyView.
The effect of demographic and lifestyle factors on IgG N‐glycosylation, which determines IgG's inflammatory response, remains poorly characterized. Aging, higher BMI, female sex, smoking, and heavy alcohol consumption are determinants of IgG N‐glycome patterns, which are indicative of inflammation. Women exhibit a distinct change in IgG N‐glycosylation
Samantha Leonard, Ralph Heijmans, Virgil A. S. H. Dalm, Silvan Licher, Jan Nouta, Steinar Gijze, David Falck, P. Martin van Hagen, Robin Peeters, Manfred Wuhrer, Layal Chaker   +10 more
wiley   +1 more source

<i>In vitro</i> characterization of a novel anti-GD2/ROR1 bispecific antibody exhibiting tumor cell killing efficacy in neuroblastoma cross-cancer activity in ROR1-positive triple-negative breast cancer. [PDF]

Transl Cancer Res
Lin T, Chen X, Huang H, Zhang J, Xu Y, Lin J.   +5 more
europepmc   +1 more source

Crescentic IgM-κ Monoclonal Immunoglobulin Deposition Disease with Thrombotic Microangiopathy in Waldenström's Macroglobulinemia: A Rare and Aggressive Monoclonal Gammopathy of Renal Significance Presentation - A Case Report and Literature Review. [PDF]

Glomerular Dis
Suttaluang C, Katavetin P, Surintrspanont J, Kanjanabuch T.   +3 more
europepmc   +1 more source

Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific immune response after vaccination and challenge. [PDF]

Discov Immunol
Herbet V, Hirchaud E, Blanchard Y, Beven V, Tranchevent LC, Jarman M, Mittal B, Deblanc C, Paboeuf F, Hammond JA, Eterradossi N, Dory D, Bonnet-Di Placido M.   +12 more
europepmc   +1 more source