Results 201 to 210 of about 62,488 (307)

Large-scale paired chain BCR analysis reveals antibody clonal family inference bias and enhances resolution with machine learning. [PDF]

PLoS Comput Biol
Wang H, Wang K, Xu Q, Cai L, Huang C, Chen L, Zang Y, Hu X, Zhang J.   +8 more
europepmc   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Optimizing the Use of Serum Immunofixation for the Detection of Monoclonal Components in Hypogammaglobulinemia: Insights From a Tertiary-Care Biochemistry Laboratory. [PDF]

Cureus
Krimi K, El Moujtahide D, Sebbar EH, Choukri M.   +3 more
europepmc   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

IgG-type lymphoplasmacytic lymphoma with light chain deposition disease. [PDF]

CEN Case Rep
Ozeki T, Ito S, Sugiura T, Yokoe Y, Yasuda K.   +4 more
europepmc   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Longitudinal evolution of rheumatoid factor-expressing lymphoma precursors in a patient with Sjögren's disease. [PDF]

J Transl Autoimmun
Lee AYS, Wang JJ, Brown DA, Reed JH.
europepmc   +1 more source

Immunoglobulin Heavy Chain Diversity Region [PDF]

, 2020
openaire   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Immunoglobulin Heavy Chain Joining Region [PDF]

, 2020
openaire   +1 more source