Results 201 to 210 of about 1,441,564 (292)

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Proteome of CD9⁺ Plasma Small Extracellular Vesicles Differentiates Stages of HPV-Associated Cervical Neoplasia from Normal Epithelium to Invasive Cancer. [PDF]

Life (Basel)
Yurin AM, Starodubtseva NL, Bugrova AE, Kononikhin AS, Silachev DN, Frankevich VE, Tokareva AO, Indeykina MI, Evtushenko EA, Yakovlev AA, Mezhevitinova EA, Nikolaev EN, Nazarova NM, Prilepskaya VN, Chernyshev VS, Sukhikh GT.   +15 more
europepmc   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Fc-engineering for improved cancer immunotherapy. [PDF]

Biochem Soc Trans
Borgman E, Le Gall C, Ploegh H, Pishesha N.   +3 more
europepmc   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Time-Dependent Voronoi Analysis of Amino Acid Side-Chain Packing in Simulations. [PDF]

J Comput Chem
Bettencourt SB, Hwang W.
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

ANARCII enables alignment-free antigen receptor numbering using a generalised language model. [PDF]

Commun Biol
Greenshields-Watson A, Agarwal P, Robinson SA, Williams BH, Gordon GL, Capel HL, Li Y, Spoendlin FC, Aguilar-Sanjuan B, Boyles F, Deane CM.   +10 more
europepmc   +1 more source

Mechanically robust biochar‐modified polystyrene foam with enhanced flame retardancy using halogen‐free additives

Polymer International, EarlyView.
Halogen‐free biocomposite polystyrene foams were fabricated via pilot‐scale supercritical CO2 extrusion using expandable graphite, melamine polyphosphate, biochar, and recycled polymer. The optimized formulation exhibited refined cellular morphology, enhanced flame retardancy (limiting oxygen index of 25%, rapid self‐extinguishing), and improved ...
Apurv Gaidhani, Harasavardanan Velumani Jayaraman, Stephan Edwards, Lauren Tribe, Paul Charpentier   +4 more
wiley   +1 more source

Transcriptomic and Proteomic Insights into Mucosal Immune Responses of Asian Seabass (<i>Lates calcarifer</i>) After Sequential Mucosal Vaccination Against Bacterial Pathogens. [PDF]

Int J Mol Sci
Rodwihok C, Thompson KD, Meachasompop P, Kumwan B, Adisornprasert Y, Chaemlek P, Srisapoome P, Thangsunan P, Thangsunan P, Buncharoen W, Kingwascharapong P, Rodkhum C, Paankhao N, Uchuwittayakul A.   +13 more
europepmc   +1 more source