Results 261 to 270 of about 136,602 (331)

Daratumumab and isatuximab differentially affect CD38 detection on plasma cells in myeloma: Anti‐CD38 nanobody (clone JK36) and CD319 combination improve flow cytometric identification of plasma cells after targeted therapies

British Journal of Haematology, EarlyView.
Daratumumab and isatuximab differentially affect plasma cell identification by anti‐CD38 detection antibodies. HB‐7 and JK36 bind to CD38 epitopes E1 and E3, respectively, and co‐staining of plasma cells in the absence of CD38‐directed drugs results in a diagonal staining pattern (top left).
Afshin Shameli, Tori Catey, Valerie Woodings, Orrin Koepke, Jonathan R. Fromm, Sindhu Cherian   +5 more
wiley   +1 more source

Renal heavy and light chain amyloidosis: A rare case report. [PDF]

Medicine (Baltimore)
Chen B, Wang J, Zang W, Wang C, Li J, Yang R.   +5 more
europepmc   +1 more source

Diagnostic and Therapeutic Aspects of Monoclonal Gammopathies of Renal Significance (MGRS): An Update. [PDF]

Diagnostics (Basel)
Netti GS, Troise D, Rossini M, Catalano V, De Luca F, Khalid J, Camporeale V, Ritrovato F, Infante B, Sanguedolce F, Stallone G, Ranieri E.   +11 more
europepmc   +1 more source

Poor prognosis of newly diagnosed multiple myeloma patients with 1p32.3 deletion in single monoallelic deletion and/or in main clone

British Journal of Haematology, EarlyView.
Summary Del(1p32.3) by FISH detection in multiple myeloma (MM) has not been routinely carried out in China. Its clinical significance was not clearly demonstrated. This study analysed clinical characteristics, treatment response and prognostic significance of del(1p32.3).
Hongying You, Weiqin Yao, Lingzhi Yan, Yingying Zhai, Zhi Yan, Jingjing Shang, Shuang Yan, Xiaolan Shi, Song Jin, Xinxin Ge, Hongjie Shen, Jinlan Pan, Depei Wu, Chengcheng Fu   +13 more
wiley   +1 more source

Immunoglobulin light chain mutational status refines IGHV prognostic value in identifying chronic lymphocytic leukemia patients with early treatment requirement. [PDF]

Leukemia
Nabki J, Al Deeban B, Sium AM, Cosentino C, Almasri M, Awikeh B, Maher N, Bellia M, Dondolin R, Mouhssine S, Talotta D, Secomandi E, Kogila S, Ghanej J, Maiellaro F, Cividini L, Rasi S, Chiarenza A, Olivieri J, Gentile M, Zaja F, Del Principe MI, Laurenti L, Bomben R, Vit F, Bittolo T, Zucchetto A, Gattei V, Gaidano G, Moia R.   +29 more
europepmc   +1 more source

Deacetylation of BAP31 by sirtuin 2 attenuates apoptosis of hepatocytes induced by endoplasmic reticulum stress, in chronic alcoholic liver injury

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Endoplasmic reticulum (ER) stress is a crucial pathogenic mechanism in alcoholic liver disease (ALD). B‐cell receptor‐associated protein 31 (BAP31) can regulate ER homeostasis and anti‐apoptosis, but the function and regulation of BAP31 in ALD are unclear.
Sai Wang, Yufeng Wang, Wen Shan, Guoyang Li, Ran Yan, Zhecheng Wang, Yan Zhao, Jihong Yao, Ning Zhang   +8 more
wiley   +1 more source

Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]

Foods
Zhou T, Zhang H, Yu X, Pan K, Yao X, Shen X, Lei H.   +6 more
europepmc   +1 more source

Polypharmacy in mice disrupts left ventricular function and structure and promotes proteome reorganisation in an age‐ and sex‐specific fashion

British Journal of Pharmacology, EarlyView.
Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran, Kevin Winardi, Scott P. Levick, Alexander Widiapradja, Gizem Gemikonakli, Susan E. Howlett, Matthew J. McKay, Mark P. Molloy, John Mach, Sarah N. Hilmer   +9 more
wiley   +1 more source

Recent developments in systemic light-chain amyloidosis prognosis and treatment. [PDF]

Future Cardiol
Ioannou A.
europepmc   +1 more source