Results 101 to 110 of about 297,267 (302)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Symptomatic hypogammaglobulinemia in infancy and childhood – clinical outcome and in vitro immune responses

BMC Family Practice, 2004
Background Symptomatic hypogammaglobulinemia in infancy and childhood (SHIC), may be an early manifestation of a primary immunodeficiency or a maturational delay in the normal production of immunoglobulins (Ig). We aimed to evaluate the natural course of
Stein Michael, Altboum Irit, Schwartz Rivka, Handzel Zeev T, Kidon Mona, Zan-Bar Israel   +5 more
doaj   +1 more source

Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations. [PDF]

Genes Immun, 2021
Collins AM, Peres A, Corcoran MM, Watson CT, Yaari G, Lees WD, Ohlin M.   +6 more
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Purification of immunoglobulin E (IgE) antibodies from sera with high IgE titers

Journal of Immunological Methods, 1995
A three stage method for the ultrapurification of polyclonal IgE from human serum is reported using anion exchange chromatography followed by monoclonal antibody based positive and negative affinity chromatography. Following dialysis of 25-100 ml of serum (2.3-14 micrograms IgE/ml, n = 4) against 0.05 M Tris pH 8, each specimen was subjected to ...
J, Kleine-Tebbe, R G, Hamilton, M, Roebber, L M, Lichtenstein, S M, MacDonald   +4 more
openaire   +2 more sources

Experiences of Immunoglobulin Therapy for Those with a Confirmed Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy: A Mixed-Methods Study with a Qualitative Patient Perspective Focus

Patient Preference and Adherence
Alphonse Hubsch,1 Sarah-Jane Cashmore,2 Rajiv Mallick,3 Ben Gibbons2 1CSL Behring, Bern, Switzerland; 2Bryter Inc., New York, NY, USA; 3Risk Sharing Solutions, Phoenixville, PA, USACorrespondence: Sarah-Jane Cashmore, Bryter Inc., 433 Broadway, New York,
Hubsch A, Cashmore SJ, Mallick R, Gibbons B   +3 more
doaj  

PURIFICATION AND PARTIAL CHARACTERIZATION OF SERUM IMMUNOGLOBULIN FROM PERSIAN STURGEON (ACIPENSER PERSICUS)

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2003
In this study, immunoglobulins from serum of Persian sturgeon (Acipenser persicus) were purified and partially characterized. Immunoglobulins were purified from the pooled sera by a combination of salt precipitation, Ion-exchange chromatography and gel ...
M. Kalbasi1; A. Mostafaei2; J. Majidi3
doaj  

Evaluation of alterations in serum immunoglobulin concentrations in components of metabolic syndrome, obesity, diabetes, and dyslipidemia

BMC Cardiovascular Disorders, 2019
Purpose Serum immunoglobulins (Igs) play a critical role in modulating the immune response by neutralizing pathogens, although little is known about the effect of Igs in development of atherosclerotic cardiovascular disease (ASCVD).
Dee Lin, Mary Barna Bridgeman, Luigi Brunetti   +2 more
doaj   +1 more source

Cloning of Size-Selected Human Immunoglobulin Heavy-Chain Rearrangements from Third Complementarity-Determining Region Fingerprint Profiles

BioTechniques, 1996
Methods have been developed to rapidly visualize the size distribution of third complementarity-determining regions (CDR3) in immunoglobulin (Ig) and T-cell receptor (TCR) molecules.
Frank M. Raaphorst, Joseph Tami, Ignacio E. Sanz   +2 more
doaj   +1 more source

Immunoglobulin (Ig)A seropositivity against SARS-CoV-2 in healthcare workers in Israel, 4 April to 13 July 2020: an observational study. [PDF]

Euro Surveill, 2021
Lustig Y, Cohen C, Biber A, Jaber H, Becker Ilany Y, Indenbaum V, Amit S, Mandelboim M, Mendelson E, Regev-Yochay G.   +9 more
europepmc   +1 more source