Results 81 to 90 of about 297,267 (302)

Prophylactic immunoglobulin therapy for pediatric congenital myotonic dystrophy

Immunological Medicine
Congenital Myotonic Dystrophy (CMD) is an autosomal dominant hereditary disease caused by mutations in the dystrophia myotonica protein kinase gene. Patients with CMD often exhibit low immunoglobulin (Ig) G levels.
Yoji Uejima, Satoshi Sato
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy. [PDF]

, 2014
Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known.
Kellermayer Miklós, Mártonfalvi, Zsolt, Mártonfalvi Zsolt, Miklós Kellermayer, Kellermayer, Miklós, Zsolt Mártonfalvi   +5 more
core   +2 more sources

Plaque reduction neutralizing antibody titers (90%) of ZIKV-IG and placebo-IG-treated animals.

, 2022
Longitudinal neutralizing antibody titers of ZIKV-IG-treated animals (red). Placebo-IG PRNT90 titers were measured at 0 and 27 dpi only (blue). Dotted vertical lines represent the time point 1 hour post-ZIKV-IG infusion for reference. Mean titers with 95%
Tulika Singh (7310102), Thaddeus G. Golos (3375128), Maria Dennis (9553613), Shantha Kodihalli (630152), Wendi Guo (13047052), Heather A. Simmons (8259912), Christina M. Newman (9553601), Phoenix M. Shepherd (7114259), Deborah M. Anderson (7833023), Sierra Rybarczyk (6597521), Sallie R. Permar (7310132), Dawn M. Dudley (9553604), Elaina Razo (9553595), Michael K. Fritsch (11210902), Emma L. Mohr (3375131), Matthew R. Semler (5029961), Kathleen M. Antony (4047928), Michelle R. Koenig (4538368), Hongyu Qiu (317690), Keisuke Yamamoto (165942), Meghan E. Breitbach (3375152), Priyadarshini Tunga (13047049), Ann Mitzey (9553598), Sarah Kohn (4047937), Andrea M. Weiler (9553607), David H. O’Connor (6639923), Jens C. Eickhoff (11210905), Andres Mejia (4379644), Laurel M. Stewart (4047931), Michele Schotzko (13047046), Xiankun Zeng (623049), Matthew T. Aliota (9519647), Thomas C. Friedrich (8321406)   +32 more
core   +1 more source

Benefits of Immunoglobulin (Ig) Replacement Therapy for Primary and Secondary Immunodeficiency in Chronic Rhinosinusitis [PDF]

, 2023
This is the first study to examine chronic rhinosinusitis (CRS) outcomes after starting immunoglobulin (Ig) replacement therapy for patients with primary (PID) and secondary immunodeficiency (SID).
Naimi, Bita, Nyquist, Gurston, Toskala, Elina, Arielle Best, Keisha, Rabinowitz, Mindy, Farquhar, Douglas, Duffy, Alexander, Hannikainen, Paavali, Garvey, Emily A., Kahn, Chase, Fung, Shirley, Rosen, Marc   +11 more
core   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Pulmonary cavitary lesions may be one of the presenting features in Ig A nephropathy

Reumatismo, 2018
Immunoglobulin A (Ig A) nephropathy is the most frequent primary glomerulonephritis. Renal limited disease is the most widespread clinical form of the disease.
B. Isci, T.S. Gamsiz, S. Kayipmaz, O. Keskin, M.E. Tezcan   +4 more
doaj   +1 more source

Diagnostic Usefulness of Varicella Zoster Virus-Specific Immunoglobulin (Ig) A and IgG in Patients With Herpes Zoster. [PDF]

J Korean Med Sci, 2023
Choi S, Moon SM, Kwon JS, Kim SH, Park SY.   +4 more
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Process steps for the fractionation of immunoglobulin (Ig) G depleted of IgA, isoagglutinins, and devoid of in vitro thrombogenicity. [PDF]

Blood Transfus, 2021
Cheng JH, Wu YW, Wang CY, Wu SS, Hong CL, Chan KW, Liao LX, Cao X, Wang B, Burnouf T.   +9 more
europepmc   +1 more source