Results 211 to 220 of about 208,254 (303)

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

Biotechnology and Bioengineering, EarlyView.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn, Hannah K. Windsor, Zachary Schmitz, Nathaniel Cheung, Ebube Agwaramgbo, Benjamin J. Hackel   +5 more
wiley   +1 more source

Venetoclax Plus CyBorD Induction Therapy and Venetoclax Maintenance Treatment for Immunoglobulin Light Chain Amyloidosis with t(11;14) Translocation. [PDF]

Curr Oncol
Garami G, Obajed Al-Ali O, Virga I, Gulyás A, Bedekovics J, Tornai I, Illés Á, Magyari F.   +7 more
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Intraoral hemorrhagic bullae as the first sign of immunoglobulin light chain amyloidosis. [PDF]

CMAJ
Dominguez-Lopez RM, Naharro-Rodriguez J.
europepmc   +1 more source

Serum Free Immunoglobulin Light Chain [PDF]

, 2020
openaire   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source

Diagnostic Utility of Relative Apical Sparing Index in Cardiac Amyloidosis Subtypes: A Comparative Study of Immunoglobulin Light Chain and Transthyretin Amyloid Cardiomyopathy. [PDF]

Echocardiography
Saijo Y, Yamada H, Yamaguchi N, Nishio S, Zheng R, Takahashi T, Hara T, Kadota M, Kawabata Y, Ueno R, Matsuura T, Ise T, Yamaguchi K, Yagi S, Soeki T, Wakatsuki T, Sata M.   +16 more
europepmc   +1 more source

Free Immunoglobulin Light Chain Measurement [PDF]

, 2020
openaire   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Immunoglobulin light chain mutational status refines IGHV prognostic value in identifying chronic lymphocytic leukemia patients with early treatment requirement. [PDF]

Leukemia
Nabki J, Al Deeban B, Sium AM, Cosentino C, Almasri M, Awikeh B, Maher N, Bellia M, Dondolin R, Mouhssine S, Talotta D, Secomandi E, Kogila S, Ghanej J, Maiellaro F, Cividini L, Rasi S, Chiarenza A, Olivieri J, Gentile M, Zaja F, Del Principe MI, Laurenti L, Bomben R, Vit F, Bittolo T, Zucchetto A, Gattei V, Gaidano G, Moia R.   +29 more
europepmc   +1 more source