Results 21 to 30 of about 208,254 (303)

AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition; a case mimicking AHL amyloidosis

BMC Nephrology, 2018
Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe, Chihiro Iwasaki, Michiyasu Hatano, Fuyuki Kametani, Masahide Yazaki, Kosaku Nitta, Michio Nagata   +6 more
doaj   +1 more source

Utility of anti-immunoglobulin IgA, IgG, IgM, Kappa, Lambda - FITC (conjugate) cocktail in routine renal pathology practice

Surgical and Experimental Pathology, 2023
Background Immunofluorescence studies on frozen sections are an essential component in the evaluation of renal biopsies. The basic panel in most centres constitutes IgG, IgA, IgM, C3c, C1q, Kappa and Lambda light chain antibody testing.
Shilpi Thakur, Balan Louis Gaspar
doaj   +1 more source

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte, Schwirzke, Marina, Weidle, Ulrich H., Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

Immunoglobulin light chains in uremia [PDF]

Kidney International, 2003
Immunoglobulin light chains (IgLCs) are produced by B cells, slightly in excess of immunoglobulin heavy chains, and therefore are present in the serum of healthy adults in free form at low concentrations. Both the kappa and lambda form of these polyclonal IgLCs are mainly metabolized by the kidney and appear under normal conditions only in small ...
openaire   +2 more sources

Rearrangement of Immunoglobulin Genes in Tumor Cells of Patients with Primary Mediastinal (Thymic) Large B-Cell Lymphoma

Клиническая онкогематология, 2019
Background. Primary mediastinal (thymic) large B-cell lymphoma (PMBCL) is a malignant tumor with large atypical lymphoid cells expressing post-germinal differentiation markers.
Yana Konstantinovna Mangasarova, Yu. V. Sidorova, A. U. Magomedova, B. V. Biderman, E. E. Nikulina, A. B. Sudarikov, A. M. Kovrigina, S. K. Kravchenko   +7 more
doaj   +1 more source

Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis.

PLoS ONE, 2020
Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis is caused by a misfolded light chain produced by a clonal population of plasma cells.
Elaine C Chen, Samuel Rubinstein, Cinque Soto, Robin G Bombardi, Samuel B Day, Luke Myers, Alexey Zaytsev, Mahsa Majedi, R Frank Cornell, James E Crowe   +9 more
doaj   +1 more source

The Immunoglobulins of Cold-Blooded Vertebrates [PDF]

, 2014
Peer reviewedPublisher ...
Chen, Clem, Cone, Cooper, Crouch, Deza, Grey, Hadji-Azimi, Hsu, Kokubu, Leslie, Magor, Malecek, Mansikka, Patel, Schaerlinger, Schaerlinger, Small, Steiner, Turchin, Wilson, Wu, Zapata   +22 more
core   +2 more sources

A tale of monoclonal immunoglobulin: Clinicopathological analysis of proliferative glomerulonephritis with monoclonal immunoglobulin deposit

Indian Journal of Pathology and Microbiology, 2021
Background: Proliferative glomerulonephritis with monoclonal immunoglobulin deposit (PGNMID) is an entity with a variable clinical and histological spectrum, which mimics immune-complex mediated glomerulonephritis on light microscopy. In this article, we
Priyanka Maity, Saugat Dasgupta, Keya Basu, Moumita Sengupta, Arpita Roy Chowdhury, Manimoy Bandopadhyay   +5 more
doaj   +1 more source

Polyclonal and monoclonal B lymphocytes response in HCV-infected patients treated with direct-acting antiviral agents [PDF]

, 2017
Hepatitis C virus (HCV) chronic infection can be associated with extrahepatic manifestations such as mixed cryoglobulinaemia and lymphoproliferative disorders that are endowed with increased rates of morbidity and all-cause mortality.
Burra, Patrizia, Farinati, Fabio, Floreani, Annarosa, Fogar, Paola, Franceschet, Enrica, Gambato, Martina, Nabergoj, Mitja, Pantano, G, Piva, Elisa, Plebani, Mario, Russo, FRANCESCO PAOLO, Schiavinato, Alvise, Tosato, Francesca, Zanetto, Alberto   +13 more
core   +1 more source

Comparison of serum free light chain and urine electrophoresis for the detection of the light chain component of monoclonal immunoglobulins in light chain and intact immunoglobulin multiple myeloma

Haematologica, 2016
Response criteria for multiple myeloma are based upon changes in monoclonal protein levels quantified using serum and/or urine protein electrophoresis.
Thomas Dejoie, Michel Attal, Philippe Moreau, Jean-Luc Harousseau, Herve Avet-Loiseau   +4 more
doaj   +1 more source