Results 111 to 120 of about 248,637 (315)

Identification and Genetic Control of two Rabbit Immunoglobulin Allotypes at a Second Light Chain Locus, the c Locus [PDF]

open access: bronze, 1969
Alice Gilman‐Sachs   +4 more
openalex   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

open access: yesAdvanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao   +15 more
wiley   +1 more source

Identification of two rate-limiting steps in the degradation of partially folded immunoglobulin light chains. [PDF]

open access: yesFront Cell Dev Biol, 2022
Mann MJ   +5 more
europepmc   +1 more source

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao   +11 more
wiley   +1 more source

AL(light chain)-amyloidogenesis by mesangial cells involves active participation of lysosomes: An ultrastructural study

open access: yesHeliyon, 2023
Amyloid formation by cells is a stepwise process that occurs in macrophages and cells capable of transforming into a macrophage phenotype. One such cell is the mesangial cell in the kidney.
Guillermo A. Herrera   +5 more
doaj  

ASSESSMENT OF THE RESIDUAL TUMOR IN PATIENTS WITH MULTIPLE MYELOMA BASED ON THE ANALYSIS OF THE FREE LIGHT CHAINS OF IMMUNOGLOBULINS IN BLOOD SERUM

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Efficiency of the multiple myeloma treatment with chemotherapy including bortezomib was assessed based on determination of the level of immunoglobulin free light chains in blood serum. The method enables estimation of changes in kinetic parameters of the
T. A. Мitina   +13 more
doaj   +1 more source

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi   +11 more
wiley   +1 more source

Light Transition Metal Monatomic Chains [PDF]

open access: yesarXiv, 2008
In this paper we investigated structural, electronic and magnetic properties of 3d (light) transition metal (TM) atomic chains using first-principles pseudopotential plane wave calculations. Periodic linear, dimerized linear and planar zigzag chain structures and their short segments consisting of finite number of atoms have been considered.
arxiv  

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