Results 91 to 100 of about 93,706 (306)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Light chain nephropathy

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2015
Light chain deposition disease (LCDD) is characterized by the tissue deposition of monotypic immunoglobulin light chains of either kappa or lambda isotype.
Sihem Darouich   +6 more
doaj   +1 more source

Long-term cultures of murine fetal liver retain very early B lymphoid phenotype. [PDF]

open access: yes, 1984
Long-term cultures of murine fetal liver have been successfully established using a modification of our in vitro bone marrow culture system (14, 15).
Denis, KA   +3 more
core  

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi   +4 more
wiley   +1 more source

Serum free light chain assays not total light chain assays are the standard of care to assess Monoclonal Gammopathies

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2016
The diagnosis of Multiple Myeloma is a challenge to the physician due to the non-specific symptoms (anemia, bone pain and recurrent infections) that are commonplace in the elderly population.
Vania Tietsche de Moraes Hungria   +3 more
doaj   +1 more source

Hybrid modeling, HMM/NN architectures, and protein applications [PDF]

open access: yes, 1996
We describe a hybrid modeling approach where the parameters of a model are calculated and modulated by another model, typically a neural network (NN), to avoid both overfitting and underfitting.
Baldi, Pierre, Chauvin, Yves
core   +1 more source

A Mechanistic Study of Bio‐Based Nanotemplated Carbon Nanofibers Derived From Water Processable Lignin Blends for Sustainable Energy Storage Applications

open access: yesAdvanced Materials, EarlyView.
As‐spun carbon materials produced from Lignosulfonate, gelatin, and alginate, selected for water solubility, and ability to produce templated sustainable carbon nanostructures. Gelatin and alginate are sacrificial during thermal processing, allowing the production of engineered high surface area nanostructures, which are further characterized for ...
Judith Miralda‐Jalle   +6 more
wiley   +1 more source

Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response. [PDF]

open access: yes, 1992
Although much has been learned about the molecular basis of immunoglobulin M (IgM) rheumatoid factors (RFs) in healthy individuals and in patients with mixed cryoglobulinemia and rheumatoid arthritis, little is known about the genetic origins of the ...
Carson, DA   +7 more
core  

Exploring the Potential of Zero‐Dimensional Carbon Nanomaterials in Photoluminescent, Electrochemiluminescent and Electrochemical Sensors

open access: yesAdvanced Materials Interfaces, EarlyView.
Zero‐dimensional carbon nanomaterials are presented as multifunctional platforms linking structure, property, and sensing performance. Surface engineering and heteroatom doping modulate electron‐transfer and luminescent behavior, enabling electrochemical, photoluminescent, and electrochemiluminescent detection. Fundamental design principles, analytical
Gustavo Martins   +8 more
wiley   +1 more source

Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis

open access: yesNature Communications
Systemic AL amyloidosis is one of the most frequently diagnosed forms of systemic amyloidosis. It arises from mutational changes in immunoglobulin light chains.
Sara Karimi-Farsijani   +11 more
doaj   +1 more source

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