Results 101 to 110 of about 3,969,240 (284)
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Haematologica, 2007 Monitoring of serum free immunoglobulin light chains (FLC) in 26 myeloma patients who achieved immunofixation negativity after allografting showed a decrease of FLC at a median of 128 days before immunofixation negativity.
Ulrike Mösbauer +5 more
doaj +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
, 2011 Bekanntermaßen haben Patienten mit chronischer Niereninsuffizienz eine erhöhte Morbidität und Mortalität. In der vorliegenden Untersuchung wurde geprüft, ob die Serumkonzentrationen an freien Leichtketten Kappa und Lambda prädiktive Faktoren für das ...
Caspari, Cristina Angelina
core +1 more source
Correlation of Immunoglobulin Free Light Chains in Risk Stratification for Chronic Obstructive Pulmonary Disease Patients [PDF]
, 2020 INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is characterized by an irreversible, progressive airflow limitation associated with abnormal inflammatory response of lungs. B cells have been suggested to contribute to the ongoing inflammation
Geethanjali, R
core
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
, 2003 A manifesto for the conference that was a collaborative effort between the Break the Chains Collective (Eugene, OR), the Anarchist Prisoner's Legal Aid Network (AKA APLAN, Portland, Or) and the National Anarchist Black Cross Network, stating that the ...
Break the Chains (Organization)
core +1 more source
Sequence analysis of variable regions of human monoclonal anti-P immunoglobulin
Zhongguo shuxue zazhi[Objective] To identify the structure of the complementarity determining region (CDRs), the V(D)J rearrangement and somatic hypermutational characteristics of the heavy and light chains of a red blood cell blood group-specific monoclonal antibody ...
GUO Zhonghui +3 more
doaj +1 more source
Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Case Reports in Oncological Medicine, 2016 Heavy chain diseases are rare variants of B-cell lymphomas that produce one of three classes of immunoglobulin heavy chains, without corresponding light chains. We describe two patients with asymptomatic heavy chain monoclonal gammopathy.
Jan Van Keer +4 more
doaj +1 more source