Results 121 to 130 of about 258,914 (247)

Increased serum free light chains precede the presentation of immunoglobulin light chain amyloidosis.

Journal of Clinical Oncology, 2014
B. Weiss, Joseph Hebreo, D. Cordaro, M. Roschewski, T. P. Baker, K. Abbott, S. Olson   +6 more
semanticscholar   +1 more source

Identification of a Carcinoembryonic Antigen Gene Family in the Rat [PDF]

, 1989
The existence of a carcinoembryonic antigen (CEA)-like gene family in rat has been demonstrated through isolation and sequencing of the N- terminal domain exons of presumably five discrete genes (rnCGM1-5).
Barnert, Sabine, Kleist, Sabine von, Kodelja, Vitam, Lucas, Kurt, Thompson, John A., Zimmermann, Wolfgang   +5 more
core  

The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region. [PDF]

, 1991
A family of chimeric immunoglobulins (Igs) bearing the murine variable region directed against the hapten dansyl linked to human IgG1, -2, -3, and -4 has been characterized with respect to binding to the human high affinity Fc gamma receptor, Fc gamma RI.
Canfield, SM, Morrison, SL
core  

Inducing the Loss of Immunoglobulin Light Chain Production and the Rearrangement of a Previously Excluded Allele in Human Plasma B Cell Lines with Concanavalin A [PDF]

, 1996
Hirofumi Tachibana, Yoshitaka Ushio, Chatchadaporn Krungkasem, Sanetaka Shirahata   +3 more
openalex   +1 more source

Isolation and characterization of a light chain variable region gene for human rheumatoid factors. [PDF]

, 1987
Previously, we isolated a Vk gene (Humkv325) from a human placenta that encodes RF light chains bearing the PSL2 and PSL3 CRI markers. Here we report the isolation and characterization of a second human Vk gene (Humkv328) that can be used for RF ...
Carson, DA, Chen, PP, Jirik, FR, Kipps, TJ, Robbins, DL   +4 more
core  

Cutaneous light chain amyloidosis and erythema elevatum diutinum as the presenting features of IgA monoclonal gammopathy: a rare case report and comprehensive literature review

Annals of Hematology
Monoclonal gammopathy (MG) associated with dermatological disorders, which is classified as monoclonal gammopathy of clinical significance (MGCS), represents a well-established complication.
Bing Han, Junfeng Zhou, Hesong Liu, Shanshan Li, Hong Wang   +4 more
doaj   +1 more source

Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins. [PDF]

Bioorg Med Chem Lett, 2020
Yan NL, Santos-Martins D, Rennella E, Sanchez BB, Chen JS, Kay LE, Wilson IA, Morgan GJ, Forli S, Kelly JW.   +9 more
europepmc   +1 more source

Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy. [PDF]

, 1988
Recently the minor B cell subpopulation that expresses the CD5 (Leu-1) antigen has been implicated as a source of IgM autoantibodies. Chronic lymphocytic leukemia (CLL), the most common leukemia in humans, represents a malignancy of small B lymphocytes ...
Carson, DA, Chen, PP, Kipps, TJ, Tomhave, E   +3 more
core  

Multiple sclerosis: assay of free immunoglobulin light chains

Annals of Clinical Biochemistry, 2017
D. Ramsden
semanticscholar   +1 more source

Primary structure of a human IgA1 immunoglobulin. V. Amino acid sequence of a human IgA lambda light chain (Bur).

, 1979
A J Infante, Frank W. Putnam
openalex   +1 more source