Results 1 to 10 of about 376,704 (295)
Process‐Scale Purification of Immunoglobulin M Concentrate [PDF]
Vox Sanguinis, 1993 AbstractAn IgM concentrate was purified from Cohn fraction III. Efficiency of euglobin precipitation was shown to be controlled by pH and ionic strength. Prekallikrein activator activity in the product was insignificant. Overall yield from the octanoic acid supernate and purity of the concentrate were 66 ± 8 (n = 16) and 50 ± 5% (n = 16), respectively.
Grace C. Tsay +4 more
openaire +2 more sources
Some of the next articles are maybe not open access.
Evolution of Conformational Flexibility of Immunoglobulin M
1975Since the initial observations of Heidelberger and Pederson (1) of a macroglobulin antibody against pneumococcus in the horse, IgM has been recognized as a major class of immunoglobulins in mammals as well as in vertebrates as phylogenetically distant as the elasmobranchii (2). In fact, IgM appears to be the first recognizable class to have evolved. It
Renata E. Cathou, David A. Holowka
openaire +3 more sources
Immunochemical studies of an immunoglobulin M-immunoglobulin G mixed cryoglobulin
Clinical Immunology and Immunopathology, 1978Abstract A mixed IgG-IgM cryoglobulin was isolated from a patient with arthritis and glomerulonephritis. Electron microscopic examination of both cryoprecipitate and glomerular deposits revealed unusual structures designated as “cylindrical and annular bodies.” The IgM component was monoclonal and had antibody activity against IgG molecules ...
A. C. Wang +2 more
openaire +3 more sources
Neutralization by Immunoglobulin M
1993The pentameric nature of IgM ensures high avidity (about 107-fold greater than Fab) for structures bearing repeated identical antigenic determinants, but in general IgM is of low specificity since its variable region genes are not subject to hypermutation modification that occurs in cells synthesizing IgG or IgA and increases the affinity of these ...
openaire +2 more sources
Nephrology, 2010
There are immunoglobulin (Ig)A nephropathy (IgAN) cases showing mesangial IgG and/or IgM deposition, however, their characteristics have remained unknown.Three hundred and eighty-four IgAN patients were divided according to the existence of mesangial IgG and/or IgM deposition: IgA deposition only (A group, n = 77); IgA and IgM deposition (AM group, n =
Ari Shimizu +5 more
openaire +2 more sources
There are immunoglobulin (Ig)A nephropathy (IgAN) cases showing mesangial IgG and/or IgM deposition, however, their characteristics have remained unknown.Three hundred and eighty-four IgAN patients were divided according to the existence of mesangial IgG and/or IgM deposition: IgA deposition only (A group, n = 77); IgA and IgM deposition (AM group, n =
Ari Shimizu +5 more
openaire +2 more sources
An allotypic marker on chicken immunoglobulin M
European Journal of Immunology, 1974AbstractAn allotypic marker, present on IgM, but not IgG, molecules in sera from chickens of the inbred CA, CB and G‐B1 lines, is described. The marker, called “C‐Ml”, is absent in sera from birds of the WA and WB lines, and its segregation in (CB × WA)F2 birds is consistent with its inheritance as a single dominant factor.
openaire +3 more sources
Isolation of Murine and Human Immunoglobulin M and Murine Immunoglobulin D
Current Protocols in Immunology, 2009AbstractThis unit describes two classical protocols for the purification of IgM—dialysis of ascites fluid, tissue culture medium, or bioreactor supernatants against distilled water to precipitate pure IgM, and ammonium sulfate precipitation. Both protocols can be followed by size‐exclusion chromatography to obtain a highly purified product.
Ashok Amin +3 more
openaire +3 more sources
Adsorptive voltammetric behaviour of immunoglobulin M
Talanta, 1991The adsorptive voltammetric behaviour of immunoglobulin M (IgM) has been investigated at the static mercury drop electrode. The stripping process yields an analytically useful signal and the detection limit is 1.2 x 10(-10)M. The adsorptive voltammetric behaviour of IgM has been compared with that of IgG and streptavidin.
Richard O'Kennedy +2 more
openaire +3 more sources
Journal of Chromatography A, 2018
This study investigated adsorption selectivity of immunoglobulin M (IgM), immunoglobulin A (IgA) and immunoglobulin (IgG) on four mixed-mode resins with the functional ligands of 4-mercatoethyl-pyridine (MEP), 2-mercapto-1-methylimidazole (MMI), 5-aminobenzimidazole (ABI) and tryptophan-5-aminobenzimidazole (W-ABI), respectively.
Shan-Jing Yao +3 more
openaire +2 more sources
This study investigated adsorption selectivity of immunoglobulin M (IgM), immunoglobulin A (IgA) and immunoglobulin (IgG) on four mixed-mode resins with the functional ligands of 4-mercatoethyl-pyridine (MEP), 2-mercapto-1-methylimidazole (MMI), 5-aminobenzimidazole (ABI) and tryptophan-5-aminobenzimidazole (W-ABI), respectively.
Shan-Jing Yao +3 more
openaire +2 more sources
ChemInform Abstract: Immunoglobulin M Determinations
ChemInform, 2010AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Dean D. Erdman, Lia M. Haynes
openaire +3 more sources