Immunoglobulin M bullous pemphigoid: An enigma [PDF]
JAAD Case Reports, 2020 Rosalie Baardman, MD +4 more
doaj +9 more sources
Immunoglobulin M Paraproteinaemias. [PDF]
Cancers (Basel), 2020 Monoclonal paraproteinaemia is an increasingly common reason for referral to haematology services. Paraproteinaemias may be associated with life-threatening haematologic malignancies but can also be an incidental finding requiring only observation ...
Girard LP +5 more
europepmc +6 more sources
Update on the hyper immunoglobulin M syndromes [PDF]
British Journal of Haematology, 2010 The Hyper‐immunoglobulin M syndromes (HIGM) are a heterogeneous group of genetic disorders resulting in defects of immunoglobulin class switch recombination (CSR), with or without defects of somatic hypermutation (SHM).
E. Davies, A. Thrasher
semanticscholar +7 more sources
Immunoglobulin M: An Ancient Antiviral Weapon – Rediscovered [PDF]
Frontiers in Immunology, 2020 Recent discoveries have shed new light onto immunoglobulin M (IgM), an ancient antibody class preserved throughout evolution in all vertebrates. First, IgM – long thought to be a perfect pentamer – was shown to be asymmetric, resembling a quasi-hexamer ...
Siqi Gong +3 more
doaj +3 more sources
Functionality of Immunoglobulin G and Immunoglobulin M Antibody Physisorbed on Cellulosic Films [PDF]
Frontiers in Bioengineering and Biotechnology, 2017 The functionality and aging mechanism of antibodies physisorbed onto cellulosic films was investigated. Blood grouping antibodies immunoglobulin G (IgG) and immunoglobulin M (IgM) were adsorbed onto smooth cellulose acetate (CAF) and regenerated ...
Ziwei Huang +2 more
doaj +5 more sources
Structural insights into immunoglobulin M
Science, 2020 Hefty structures of IgA and IgM complexes Immunoglobulin M (IgM) and IgA are antibody isotypes that can form higher-order secretory complexes (sIgM and sIgA), which allows them to effectively bind and neutralize antigens with low-affinity repetitive ...
Yaxin Li +11 more
semanticscholar +4 more sources
Immunoglobulin M Monoclonal Gammopathies of Clinical Significance [PDF]
Frontiers in Oncology, 2022 Immunoglobulin M monoclonal gammopathy of undetermined significance (MGUS) comprises 15-20% of all cases of MGUS. IgM MGUS is distinct from other forms of MGUS in that the typical primary progression events include Waldenstrom macroglobulinaemia and ...
Louis-Pierre Girard +6 more
doaj +2 more sources
Immunoglobulin M perception by FcμR
Nature, 2023 L'immunoglobuline M (IgM) est le premier anticorps à émerger au cours du développement embryonnaire et de la réponse immunitaire humorale1. Les IgM peuvent exister sous plusieurs formes distinctes, y compris les IgM monomériques liées à la membrane dans le complexe du récepteur des cellules B (BCR), les IgM pentamériques et hexamériques dans le sérum ...
Yaxin Li +6 more
semanticscholar +3 more sources
Serum immunoglobulin M concentration is positively related to metabolic syndrome in an adult population: Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) Cohort Study. [PDF]
PLoS ONE, 2014 Persistent low-grade systemic inflammation has been increasingly recognized as a common pathological process, and an important contributing factor to cardiovascular diseases and its risk factor, metabolic syndrome.
Kun Song +11 more
doaj +2 more sources
Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. [PDF]
Nat Commun, 2022 Chen Q +4 more
europepmc +2 more sources