Results 61 to 70 of about 411,227 (271)

Effect of Colostral Immunoglobulin G1 and Immunoglobulin M Concentrations on Immunoglobulin Absorption in Calves

Journal of Dairy Science, 1985
Twenty-three calves were fed colostrum at 110 ml/kg body weight divided into two feedings at 1 and 13 h of age. The concentrations of immunoglobulins were measured in the colostrum fed and in the calves' sera following colostrum feeding. Apparent efficiency of immunoglobulin absorption was calculated for each calf.
T E, Besser, A E, Garmedia, T C, McGuire, C C, Gay   +3 more
openaire   +3 more sources

Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient‐derived xenograft models

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma patient‐derived xenografts (PDAC‐PDXs) engrafted orthotopically in the pancreas of immunodeficient mice retain the main genetic and histopathological characteristics of the original human tumors. A 294 stroma gene signature differentiates between PDAC‐PDXs that are responsive to gemcitabine plus nab‐paclitaxel versus ...
Alessia Anastasia, Laura Formenti, Paola Ostano, Lucia Minoli, Andrea Resovi, Lavinia Morosi, Claudia Fioravanti, Edoardo Micotti, Cristina Matteo, Eugenio Scanziani, Giovanna Chiorino, Raffaella Giavazzi, Carmen Ghilardi, Dorina Belotti   +13 more
wiley   +1 more source

Serological Evaluation of Anti-Toxoplasma gondii Antibodies in Patients with Acute Leukemia and Lymphoma through Chemotherapy

Iranian Journal of Parasitology, 2020
Background: Toxoplasma gondii is a protozoan parasite that belongs to the family Coccidae. We aimed to evaluate IgG avidity and the changes of anti-Toxoplasma immunoglobulins M (IgM) and G (IgG) in patients with acute leukemia and lymphoma.
Fatemeh TABATABAIE, Taher ELMI, Majid KHANMOHAMMADI, Lame AKHLAGHI, Mahmoud MAHAMI-OSKOUEI, Mehdi ARSHADI   +5 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

The effect of litter size and gender on immunoglobulins and oxidative stress in damascus goats [PDF]

Eurasian Journal of Veterinary Sciences
Aim: The aim of this study is to investigate the effects of litter size (singleton-twin) and gender on the immunoglobulin level and oxidative stress in Damascus goats. Materials and Methods: Blood samples were taken with in 20 minutes after delivery from
Mehmet Aköz, İbrahim Aydın, Özcan Barış Çitil   +2 more
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China

Virology Journal, 2021
Background This cohort study was designed to investigate the prevalence of and potential risk factors of HEV infection in a large multi-ethnic youth cohort in China. Methods Blood samples were collected from participants (n = 6269) and serum was isolated.
Huixia Li, Yinxia Zhang, Zhongren Ma, Zewen Liu, Aqsa Ikram, Lijiang Liu, Guoqin Zhao, Qiuwei Pan, Zulqarnain Baloch   +8 more
doaj   +1 more source

Lack of evidence for a substantial rate of templated mutagenesis in B cell diversification [PDF]

arXiv, 2020
B cell receptor sequences diversify through mutations introduced by purpose-built cellular machinery. A recent paper has concluded that a "templated mutagenesis" process is a major contributor to somatic hypermutation, and therefore immunoglobulin diversification, in mice and humans.
arxiv  

Diagnostic significance of immunoglobulin M antibodies to Toxoplasma gondii detected after separation of immunoglobulin M from immunoglobulin G antibodies [PDF]

Journal of Clinical Microbiology, 1980
Failure to demonstrate immunoglobulin M (IgM) antibodies by indirect immunofluorescence (IgM-IFA) in sera from some patients with acute acquired toxoplasmosis has recently been attributed to an inhibitory effect of high titers of IgG antibodies in these sera (Pyndiah et al. J. Clin. Microbiol. 9:170-174, 1979).
G A Filice, A S Yeager, Jack S. Remington   +2 more
openaire   +3 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source