Results 111 to 120 of about 89,290 (305)

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Characterization of recombinant wild-type and nontoxigenic protein A from Staphylococcus pseudintermedius

Virulence, 2018
Background: Staphylococcus pseudintermedius is an opportunistic pathogen that is the major cause of pyoderma affecting dogs. Conventional antimicrobial treatment for infections caused by this organism have failed in recent years due to widespread ...
Mohamed A. Abouelkhair, David A. Bemis, Stephen A. Kania   +2 more
doaj   +1 more source

Safety profile and practical considerations of monoclonal antibody treatment

Neurología (English Edition), 2013
Introduction: Monoclonal antibodies (mAb) are immunoglobulins specially designed to act against specific targets, in such a way that their administration stops a specific pathogenic process, stimulates a particular cellular action, or changes a cell ...
B. Casanova Estruch
doaj   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. [PDF]

, 2013
Bispecific antibodies are considered as a promising class of future biotherapeutic molecules. They comprise binding specificities for two different antigens, which may provide additive or synergistic modes of action.
Duerr, Harald, Kettenberger, Hubert, Thomas, Markus, Imhof-Jung, Sabine, Fenn, Sebastian, Christian B Schiller, Harald Duerr, Julia J Griese, Griese, Julia J., Sebastian Fenn, Schiller, Christian B., Regula, Joerg Thomas, Sebastian Fenn, Schaefer, Wolfgang, Christian Klein, Klein, Christian, Christian Gassner, Hubert Kettenberger, Markus Thomas, Gassner, Christian, Julia J. Griese, Hopfner, Karl Peter, Wolfgang Schaefer, Christian B. Schiller, Karl-Peter Hopfner, Moelleken, Joerg, Hopfner, Karl-Peter, Joerg Moelleken, Joerg Thomas Regula, Sabine Imhof-Jung   +29 more
core   +1 more source

Sequence analysis of immunoglobulin variable region genes that encode autoantibodies expressed by lymphomas of mucosa associated lymphoid tissue

, 1996
Aim: To determine whether the immunoglobulin genes used by three gastric mucosa associated lymphoid tissue type lymphomas with known autoreactivity are mutated from germline as mutation from germline is an indicator of exposure to a mutational mechanism ...
Stevenson, F. K., Hussell, T.; id_orcid, Isaacson, P. G., Chapman, C. J., Spencer, J., Dünn-Walters, D. K.   +5 more
core   +1 more source

Segmental duplication as one of the driving forces underlying the diversity of the human immunoglobulin heavy chain variable gene region

BMC Genomics, 2011
Background Segmental duplication and deletion were implicated for a region containing the human immunoglobulin heavy chain variable (IGHV) gene segments, 1.9III/hv3005 (possible allelic variants of IGHV3-30) and hv3019b9 (a possible allelic variant of ...
Gao Richeng, Shen Li, Hu Guohong, Chimge Nyam-Osor, Wang Hui-Yun, Cui Xiangfeng, Pramanik Sreemanta, Li Honghua   +7 more
doaj   +1 more source

In Situ Amine Formation to Modulate MOF‐Derived PdIn N‐Doped Carbon Catalysts

Advanced Materials, EarlyView.
An amine‐assisted approach converts PdIn‐MOF into PdIn intermetallic nanoparticles embedded in N‐doped carbon. In situ‐generated amines trigger early Pd nucleation, producing smaller PdIn domains than direct pyrolysis. Amine sterics and basicity tune composition and particle size, while solvent and amine co‐determine textural features.
Gonzalo Egea, Jordan Santiago Martinez, M. Asunción Molina, Jaime Mazarío, Lucy Costley‐Wood, Christian Cerezo‐Navarrete, Carlo Marini, Eduardo Villalobos‐Portillo, Andrew M. Beale, Pascual Oña‐Burgos   +9 more
wiley   +1 more source

Somatic hypermutation of immunoglobulin variable region genes: Focus on follicular lymphoma and multiple myeloma

, 1998
Analysis of the rearranged immunoglobulin variable region gene hypermutation has prodded important information concerning the clonal history and ontogenetic origin of various B-cell lymphoproliferative disorders.
Kosmas, C., Yataganas, X., Papadaki, T., Stamatopoulos, K., Belessi, C., Loukopoulos, D., Anagnostou, D.   +6 more
core  

Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region.

, 1991
15 immunoglobulin heavy chain constant (CH) and variable region (VH) polymorphisms were selected to span the entire length of the heavy chain cluster.
G C Ebers, Ebers, GC, Ebers, George, Cox, DW, M A Walter, D W Cox, W T Gibson, Walter, MA, Gibson, WT   +8 more
core   +1 more source