Results 171 to 180 of about 326,951 (318)

Shared molecular profiles of anti-PL12 autoantibodies in anti-synthetase syndrome. [PDF]

Rheumatology (Oxford)
Ali SB, Troelnikov A, Amour B, Hender L, Beroukas D, Chataway T, Limaye V, Gordon TP, Wang JJ.   +8 more
europepmc   +1 more source

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

Advanced Science, EarlyView.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo, Haixiao Zhang, Kaiting Tang, Yiming Wang, Huajiang Dong, Wei Qi, Lingling Shan, Yue Tan, Liping Zhao, Jun Shi, Erlie Jiang, Jing Pan, Xiaoming Feng   +12 more
wiley   +1 more source

Genomic analysis of Canadian children with food allergies points to the immunoglobulin heavy chain gene locus. [PDF]

Pediatr Allergy Immunol
Madore AM, Lavoie MÈ, Boucher-Lafleur AM, Gagnon-Brassard F, Gilbert N, Bégin P, Lavoie S, Rochefort-Beaudoin C, Nuncio-Naud C, Parizeault G, Morin C, Laprise C.   +11 more
europepmc   +1 more source

Retention of an idiotypic determinant in a human B-cell lymphoma undergoing immunoglobulin variable-region mutation.

Proceedings of the National Academy of Sciences of the United States of America, 1987
S. Kon, S. Levy, R. Levy
semanticscholar   +1 more source

Mouse Immunoglobulin Heavy Chains Are Coded by Multiple Germ Line Variable Region Genes

, 1974
P A Barstad, Vincent Farnsworth, Martin Weigert, Melvin Cohn, Leroy Hood   +4 more
openalex   +2 more sources

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Conformation-aware structure prediction of antigen-recognizing immune proteins. [PDF]

MAbs
Dreyer FA, Ludwiczak J, Martinkus K, Abanades B, Alberstein RG, Kessel P, Rao P, Lee JH, Bonneau R, Watkins AM, Seeger F.   +10 more
europepmc   +1 more source

Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities.

Journal of Clinical Investigation, 1986
M. Monestier, A. Manheimer-Lory, B. Bellon, C. Painter, H. Dang, N. Talal, M. Zanetti, R. Schwartz, D. Pisetsky, R. Kuppers   +9 more
semanticscholar   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Stratification of systemic lupus erythematosus with IGHV4-34 in unswitched memory B cells. [PDF]

Rheumatology (Oxford)
Ushijima TS, Teruya H, Abe T, Itamiya T, Ota M, Okamura T, Fujio K.   +6 more
europepmc   +1 more source